Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
MedComm, Volume 6, Issue 8, August 2025.We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li +8 more
wiley +1 more source
Indentation toughness of Al2O3-CNT nanocomposites [PDF]
, 2011 In the last few years new ceramic/carbon nanotube composites have been developed and a number of authors have reported improved mechanical and functional properties in the case of ceramic/CNT composites compared to the monolithic materials.
Dusza, Ján +3 more
core
NMR in Biomedicine, Volume 38, Issue 8, August 2025.A new CEST analysis approach, named double‐step R1rho‐based Lorentzian fitting (DROF), with initial value randomization, was developed for extracting multiple CEST contrasts at 3 T. The improved specificity and stability of DROF over existing methods were confirmed through simulation and in vivo human data, utilizing a newly proposed evaluation ...
Huabin Zhang +7 more
wiley +1 more source
Discospondylitis as a consequence of jugular vein septic thrombophlebitis in a Standardbred gelding
Equine Veterinary Education, Volume 37, Issue 8, Page e159-e165, August 2025.Summary This report describes the identification of C7‐T1 discospondylitis on myelography and confirmed on postmortem computed tomography and necropsy in a 4‐year‐old Standardbred gelding as the consequence of jugular vein catheterisation and secondary septic thrombophlebitis. Staphylococcus aureus was isolated from both sites.
F. Payette +4 more
wiley +1 more source
Orthopaedic Surgery, Volume 17, Issue 8, Page 2479-2485, August 2025.Anterior controllable antedisplacement and fusion (ACAF) is an effective strategy in treating cervical ossification of the posterior longitudinal ligament (C‐OPLL). The controllable antedisplacement of vertebrae‐OPLL complex (VOC) through screws is both the most critical and technically challenging procedure.
Qilin Lu +4 more
wiley +1 more source
A novel methodology for measurement of the intradiscal pressure and height disc variation of intervertebral disc under compression [PDF]
, 2013 The intervertebral disc (IVD) is subjected to several types of loading during daily routine events. However, the overloading on this structure induces higher intradiscal pressure (IDP), which could cause severe damage on its structure.
Araújo, Ângelo Rafael Gomes +3 more
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In vitro measurement of nucleus pulposus swelling pressure: A new technique for studies of spinal adaptation to gravity [PDF]
Swelling of the intervertebral disc nucleus pulposus is altered by posture and gravity. We have designed and tested a new osmometer for in vitro determination of nucleus pulposus swelling pressure.
Ballard, R. +7 more
core +1 more source
Exploring the biomechanical mechanisms of cervical rotation manipulation in different lateral bending positions: a finite element analysis. [PDF]
BMC Musculoskelet DisordWeng R +10 more
europepmc +1 more source
Osteoporosis in adjacent cervical segments exacerbates disc herniation. [PDF]
Sci RepWang B +5 more
europepmc +1 more source
When a herniated disc masquerades as a tumor: Latero-posterior epidural migration mimicking cauda equina neoplasm-A case report and review. [PDF]
Radiol Case RepBorni M +6 more
europepmc +1 more source