Results 51 to 60 of about 9,151 (264)

Posterior Epidural Migration of a Lumbar Intervertebral Disc Fragment Resembling a Spinal Tumor: A Case Report [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2018
Posterior epidural migration of a lumbar intervertebral disc fragment (PEMLIF) is uncommon because of anatomical barriers. It is difficult to diagnose PEMLIF definitively because of its relatively rare incidence and the ambiguity of radiological findings
Hyojun Kim   +10 more
doaj   +1 more source

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

open access: yesAdvanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh   +8 more
wiley   +1 more source

Detrimental Effect of Low-Magnitude High-Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment. [PDF]

open access: yesJOR Spine
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jansen JU   +9 more
europepmc   +2 more sources

Allograft intervertebral disc transplantation in the sheep:an assessment of the potential for allograft disc replacement [PDF]

open access: yes, 1995
STUDY DESIGN: An allograft intervertebral disc transplantation procedure was carried out in a total of twenty 2-year old Merino wethers. OBJECTIVE: The aims of this study were to test the viability and integrity of an intervertebral disc following ...
Mario, Penta
core  

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

Not all lumbar herniated discs cause low back pain

open access: yesHorizonte Médico, 2017
After a long series of terms used to define the displacement of disc material (either the nucleus pulposus or the fibrous ring), herniated discs were classified as bulging, focal protrusion, extrusion and sequestration. Herniated discs represent from 1%
Delia Gil Huayanay   +2 more
doaj   +1 more source

Biomechanical evaluation of a novel intervertebral disc repair technique for large box-shaped ruptures

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Objective: The purpose of this study was to analyze the feasibility of repairing a ruptured intervertebral disc using a patch secured to the inner surface of the annulus fibrosus (AF).
Mao-Dan Nie   +4 more
doaj   +1 more source

Statistical factorial analysis on the poroelastic material properties sensitivity of the lumbar intervertebral disc under compression, flexion and axial rotation

open access: yes, 2009
A statistical factorial analysis approach was conducted on a poroelastic finite element model of a lumbar intervertebral disc to analyse the influence of six material parameters (permeabilities of annulus, nucleus, trabecular vertebral bone, cartilage ...
Planell Estany, Josep Anton   +2 more
core   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

open access: yesAdvanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao   +14 more
wiley   +1 more source

Mechanical influence of facet tropism in patients with chronic discogenic pain disorder

open access: yesBone & Joint Research
Aims: The presence of facet tropism has been correlated with an elevated susceptibility to lumbar disc pathology. Our objective was to evaluate the impact of facet tropism on chronic lumbosacral discogenic pain through the analysis of clinical data and ...
Jun Y. Lee   +3 more
doaj   +1 more source

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