Results 121 to 130 of about 709,562 (247)

Molecular and Immunohistochemical Analyses of PLIN4 in the Spinal Cord and Brain During the Development of Electroacupuncture‐Induced Analgesic Tolerance in Mice

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Repeated electroacupuncture induced analgesic tolerance and increased Plin4 expression, particularly in spinal dorsal horn neurons. Intrathecal Plin4 knockdown delayed tolerance development and increased pain threshold, while Plin4 expression was positively associated with lipid droplet formation in N2a cells. ABSTRACT Background Electroacupuncture (EA)
Shao‐Jia Jiang, Shi‐Ya Cao, Ming‐Fei Fan, Hao Li, Rui‐Ling Yin, Qiang‐Hui Lei, Sha Nan, Hao‐Long Wang, Zi‐Hui Cai, Ya‐Ya Jiao, Fei Huang, Yi Ding, Xiao‐Shu Zhou, Xin‐Yue Chai   +13 more
wiley   +1 more source

Optimizing lumbar therapy: a biomechanical study of oblique pulling manipulation under different postures. [PDF]

BMC Complement Med Ther
Wang Y, Yu A, Jin L, Liu W, Chen D, Cao Y, Gao K.   +6 more
europepmc   +1 more source

A Mechanism‐Based Framework for Anti‐Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell‐Based Interventions

Aging Cell, Volume 25, Issue 9, September 2026.
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li, Yankai Wang, Gelin Wang, Jiguo Chen, Song Huang   +4 more
wiley   +1 more source

Three-dimensional finite element analysis of translaminar lag screw designs for L5 bilateral spondylolysis. [PDF]

Front Bioeng Biotechnol
Li F, Tan X, Zhang T, Liu H, Li S.
europepmc   +1 more source

Midlife Growth Hormone Receptor Ablation Extends Healthy Lifespan and Induces Sex‐Specific Hepatic Transcriptional Changes at Single‐Cell Resolution

Aging Cell, Volume 25, Issue 9, September 2026.
Reducing growth hormone receptor signaling beginning in middle age is sufficient to extend lifespan in both sexes while preserving metabolic and physical function, particularly in males. Single‐nucleus RNA sequencing reveals sex‐specific hepatic transcriptional remodeling associated with these longevity benefits. ABSTRACT Suppression of growth hormone (
Silvana Duran‐Ortiz, Edward O. List, Jonathan A. Young, Yuji Ikeno, Shouan Zhu, Todd McHugh, Patrick M. O'Connor, Minhoo Kim, Bérénice A. Benayoun, Fabian Benencia, Reetobrata Basu, Emmanuel A. Gotte, Darlene E. Berryman, John J. Kopchick   +13 more
wiley   +1 more source

Structural changes occurring at the surgical site long after hemilaminectomy in small-breed dogs with type I thoracolumbar intervertebral disk herniation. [PDF]

J Vet Med Sci
Sakaguchi Y, Nishida H, Tanaka H, Kitamura M, Nakayama M.   +4 more
europepmc   +1 more source

Diagnostic tools and imaging methods in intervertebral disk degeneration.

, 2011
Low back pain has a negative impact on the economy and society. Intervertebral disk degeneration is linked to the occurrence of low back pain. MRI provides three-dimensional morphologic and biochemical information regarding the status of the disk.
Majumdar, S;Link, TM;Steinbach, LS;Hu, S;Kurhanewicz, J
core  

Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging

Aging Cell, Volume 25, Issue 9, September 2026.
The beneficial gut bacterium Akkermansia muciniphila (AKK) declines with age but is enriched in healthy centenarians. Supplementation of AKK extends healthspan and alleviates age‐related decline through direct host–microbe interactions and its bioactive derivatives, which collectively enhance gut barrier integrity, restore metabolic homeostasis ...
Ting Zhang, Jinyuan Niu, Xiaoyu Hu, Zhiang Hu, Yuan Gao, Jialiang Liu, Ning Chen, Yaomin Hu   +7 more
wiley   +1 more source

Endoscopic transforaminal discectomy for far lateral disc herniation at L3-L4: A 2-dimensional operative video. [PDF]

Surg Neurol Int
Ratnaparkhi A, Levy AS, Shah KH, Burks SS.   +3 more
europepmc   +1 more source

Harnessing Metabolic Priming to Engineer Human Nucleus Pulposus Macromass Overcoming Scalability‐Phenotype Tradeoff

Cell Proliferation, Volume 59, Issue 9, September 2026.
Human platelet lysate acts as a metabolic primer for hNPCs, enhancing fatty acid oxidation to drive proliferation while preserving phenotype. This enables construction of high‐quality, large‐size macromasses without necrotic defects, demonstrating exceptional efficacy in repairing degenerated discs in situ and providing a novel paradigm for ...
Yingbo Wang, Ou Hu, Jian Wu, Sha Huang, Peng Lin, Pulin Yan, Yangyang Li, Huaijian Jin, Yutong Wu, Jun Zhu, Jungang Pu, Bo Hu, Jian He, Yibo Gan, Peng Liu   +14 more
wiley   +1 more source