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Intestinal adaptation in short bowel syndrome
Regaining enteral autonomy after extensive small bowel resection is dependent on intestinal adaptation. This adaptational process is characterized by hyperplastic growth of the remaining gut, which is accompanied by both an increase of cell division at the level of the crypt cells and by an increased rate of programmed cell death (apoptosis).
Welters, C.F.M. +3 more
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Mechanisms of intestinal adaptation. [PDF]
Following loss of functional small bowel surface area due to surgical resection for therapy of Crohn's disease, ischemia, trauma or other disorders, the remnant gut undergoes a morphometric and functional compensatory adaptive response which has been best characterized in preclinical models.
Rubin DC, Levin MS.
europepmc +4 more sources
Medical Nutrition Therapy in Short Bowel Syndrome and Food Interventions in Intestinal Adaptation
The 'normal' length of the small intestine ranges from 320 to 800 cm. short bowel syndrome is defined as the small bowel length less than 200 cm. Short bowel syndrome is a clinical manifestation that occurs mainly after anatomical and / or functional ...
Ebru KOPTAGEL, Hülya KAMARLI ALTUN
doaj +1 more source
Use of Teduglutide in Children With Intestinal Failure: A Systematic Review
Background and ObjectivesShort-bowel syndrome (SBS) results from the loss of a significant portion of the small intestine leading to a state of malabsorption.
Francesca Gigola +8 more
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Ghrelin Levels in Children With Intestinal Failure Receiving Long-Term Parenteral Nutrition
BackgroundChildren with intestinal failure (IF) require parenteral nutrition (PN). Transition to oral and enteral nutrition (EN) can be difficult also due to abnormal gastrointestinal motility.
Lotte E. Vlug +11 more
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Background. Short bowel syndrome, or short intestine, as a rule, is a consequence of extensive intestinal resection, usually of the iliac and skinny sections, when no more than 115-200 cm remains from the original length (on average in the population of ...
E. M. Kagarmanova
doaj +1 more source
The article presents an overview of current trends in the approach to the treatment of patients with short bowel syndrome, including examples of children's patients registered in the palliative care service for children of the Tyumen region.
E. P. Tropina, V. A. Zmanovskaya
doaj +1 more source
Intestinal adaptation after massive intestinal resection [PDF]
Abstract Patients with short bowel syndrome require long term parenteral nutrition support. However, after massive intestinal resection the intestine undergoes adaptation and nutritional autonomy may be obtained. Given that the complications of parenteral nutrition may be life threatening or result in treatment failure and the need for ...
Weale, AR +3 more
openaire +3 more sources
Analysis of risk factors for neonatal short bowel syndrome in two tertiary centers in Brazil
Introduction: Short bowel syndrome (SBS) is defined as a severe reduction in intestinal mucosal absorption secondary to reduced intestinal functional area.
Wellen Cristina Canesin +7 more
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Background: Gastrointestinal mucositis occurs as a consequence of cytotoxic treatment. Quercetin (QCT) is a bioflavonoid that exerts significant antioxidant activity and anti-inflammatory as well as anti-malignancy properties.
Igor Sukhotnik +5 more
doaj +1 more source

