Results 271 to 280 of about 352,113 (307)

Intestinal epithelial barrier functions in ageing

Ageing Research Reviews, 2019
The intestinal epithelial barrier protects the mucosa of the gastrointestinal (GI)-tract and plays a key role in maintaining the host homeostasis. It encompasses several elements that include the intestinal epithelium and biochemical and immunological products, such as the mucus layer, antimicrobial peptides (AMPs) and secretory immunologlobulin A ...
Jacopo J V, Branca, Massimo, Gulisano, Claudio, Nicoletti   +2 more
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Bacteria breach intestinal barriers

Science, 2014
Gut Microbiota In an ironic complication of liver cirrhosis, beneficial microbes can escape from the gut and cause serious infections—or even death. Balmer et al. now show that the blood vessels of the healthy liver form a barrier to runaway gut bacteria.
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Intestinal Barrier Function and Neurodegenerative Disease

CNS & Neurological Disorders - Drug Targets
Abstract: Neurodegenerative diseases are caused by the loss of neurons and/or their myelin sheaths, which deteriorate over time and become dysfunctional. Alzheimer's disease, Parkinson's disease, and multiple sclerosis are among the most prominent neurodegenerative diseases that affect millions of older adults worldwide.
Shijing, Wu, Liangfang, Yang, Yiwei, Fu, Zhimin, Liao, De, Cai, Zhou, Liu   +5 more
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Improvement of a ‘Leaky' Intestinal Barrier

Digestive Diseases, 2017
In Crohn's disease, the mucus layer appears to be defective in terms of low defensin levels and lack of antibacterial activity. These deficiencies actually explain the Montreal phenotypes and the stable localization of disease in the terminal ileum with low α-defensins from Paneth cells and/or low β-defensins in colonic disease, respectively ...
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Intestinal barrier protection

Nature Reviews Immunology, 2022
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INSECTS' INTESTINAL BARRIER AGAINST INFECTION

Journal of Experimental Biology, 2012
![Figure][1] The enormously large and hence vulnerable surface of the vertebrate gastrointestinal tract is largely protected from pathogenic micro-organisms by a mucous matrix made of water, glycoproteins and antimicrobial substances.
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Butyrate benefits the intestinal barrier

Science Signaling, 2015
Microbial-produced butyrate promotes intestinal epithelial barrier function by stabilizing HIF.
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The blood–tumour barrier in cancer biology and therapy

Nature Reviews Clinical Oncology, 2021
Patricia S Steeg
exaly  

Impact of enteric bacterial infections at and beyond the epithelial barrier

Nature Reviews Microbiology, 2022
Ashleigh P Rogers, Steven J Mileto, Dena Lyras   +2 more
exaly  

Intestinal barrier loss in sepsis

Netherlands journal of critical care, 2011
The intestinal mucosa is responsible for the absorption of nutrients from the lumen. In addition, it has the challenging task to provide an effective barrier between the potentially toxic luminal content (external environment) and the host (internal environment).
Thuijls, G., Derikx, J. P. M., Grootjans, J., Buurman, W. A., van Waardenburg, D. A.   +4 more
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