Results 51 to 60 of about 9,941,870 (340)

The impact of small intestinal bacterial overgrowth on the efficacy of fecal microbiota transplantation in patients with chronic constipation

mBio
To investigate the impact of Small Intestinal Bacterial Overgrowth (SIBO) on the efficacy of Fecal Microbiota Transplantation (FMT) in patients with chronic constipation, our research team included 218 patients with chronic constipation treated with FMT.
Le Wang, Yue Xu, Long Li, Bo Yang, Di Zhao, Chen Ye, Zhiliang Lin, Jiaqu Cui, Yunkun Liu, Wanyong Zhu, Ning Li, Hongliang Tian, Qiyi Chen   +12 more
doaj   +1 more source

Metabolism-Associated Molecular Classification of Colorectal Cancer

Frontiers in Oncology, 2020
The high heterogeneity of colorectal cancer (CRC) is the main clinical challenge for individualized therapies. Molecular classification will contribute to drug discovery and personalized management optimizing. Here, we aimed to characterize the molecular
Meng Zhang, Meng Zhang, Hai-zhou Wang, Hai-zhou Wang, Ru-yi Peng, Ru-yi Peng, Fei Xu, Fei Xu, Fan Wang, Fan Wang, Qiu Zhao, Qiu Zhao   +11 more
doaj   +1 more source

Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases

Biomedicines, 2022
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a critical player in gut homeostasis maintenance as it ensures the complex crosstalk between gut microbes (both commensals and pathogens) and the host immune ...
C. Stolfi, C. Maresca, G. Monteleone, F. Laudisi   +3 more
semanticscholar   +1 more source

Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders

Population Ecology, EarlyView.
We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa, Andrea Costa, Sebastiano Salvidio   +2 more
wiley   +1 more source

Diet was less significant than physical activity in the prognosis of people with sarcopenia and metabolic dysfunction-associated fatty liver diseases: Analysis of the National Health and Nutrition Examination Survey III

Frontiers in Endocrinology, 2023
BackgroundSarcopenia is prevalent in metabolic dysfunction-associated fatty liver diseases (MAFLD), and the primary treatment for both diseases is lifestyle modification.
Yun Yi, Yun Yi, Chun Wang, Chun Wang, Yang Ding, Yang Ding, JiangHua He, JiangHua He, YuQing Lv, YuQing Lv, Ying Chang, Ying Chang   +11 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The Intestinal Microbiota in Metabolic Disease [PDF]

Nutrients, 2016
Gut bacteria exert beneficial and harmful effects in metabolic diseases as deduced from the comparison of germfree and conventional mice and from fecal transplantation studies. Compositional microbial changes in diseased subjects have been linked to adiposity, type 2 diabetes and dyslipidemia. Promotion of an increased expression of intestinal nutrient
Woting, Anni, Blaut, Michael
openaire   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Prevalence, Abundance, and Virulence of Adherent-Invasive Escherichia coli in Ulcerative Colitis, Colorectal Cancer, and Coeliac Disease

Frontiers in Immunology, 2022
Background & AimsAdherent-invasive E. coli (AIEC) has largely been implicated in the pathogenesis of Crohn’s disease (CD). E. coli strains with similar genetic backgrounds and virulence genes profiles have been associated with other intestinal ...
Mireia López-Siles, Carla Camprubí-Font, Eva M. Gómez del Pulgar, Miriam Sabat Mir, David Busquets, Yolanda Sanz, Margarita Martinez-Medina   +6 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source