Results 71 to 80 of about 9,941,870 (340)

Intestinal Perforations in Behçet’s Disease [PDF]

open access: yesJournal of Gastrointestinal Surgery, 2007
Behçet's disease accompanied by intestinal involvement is called intestinal Behçet's disease. The intestinal ulcers of Behçet's disease are usually multiple and scattered and tend to perforate easily, so that many patients require emergency operation.
Shao-Jiun Chou   +6 more
openaire   +3 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

The effect of incubator humidity on morbidity and mortality in preterm infants: a systematic review

open access: yesBMC Pediatrics
Purpose To assess the association between different incubator humidity levels and clinical outcomes in preterm infants. Background Since there is no well-accepted standard for delivery of incubator humidity for preterm infants.
Zhiqin Chen   +4 more
doaj   +1 more source

Diseases of the Large Intestine

open access: yesCleveland Clinic Journal of Medicine, 1932
Diseases and abnormalities of the large intestine are far too numerous to be described in one paper; I shall discuss, therefore, only the more common conditions that may be encountered in the routine examination of the gastro-intestinal tract. The normal contour and position of the colon, as well as many of the abnormal positions that it may assume ...
openaire   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

open access: yesInternational Journal of Molecular Sciences, 2017
Glutamine, the most abundant free amino acid in the human body, is a major substrate utilized by intestinal cells. The roles of glutamine in intestinal physiology and management of multiple intestinal diseases have been reported.
Min-Hyun Kim, Hyeyoung Kim
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Intestinal manifestations of Behçet's disease [PDF]

open access: yesTerapevticheskii arkhiv, 2019
Behçet's disease (BD) is a systemic vasculitis of unknown origin, characterized by recurrences of the ulcerative process in the oral cavity and on the genitals, inflammatory damage of the eyes, joints, vessels and other organs. The severity and prognosis of BD determines organ pathology.
L P Orlova   +4 more
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

microRNAs as therapeutic targets in intestinal diseases

open access: yesExRNA, 2019
Intestinal diseases, which primarily include inflammatory bowel disease (IBD), colorectal cancer (CRC) and colitis associated cancer (CAC), are believed to develop as a result of heredity transmit, autoimmune disorders, environmental factors and ...
Chen Wang, Jiangning Chen
semanticscholar   +1 more source

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