Results 1 to 10 of about 196,149 (179)

Adenosine in Intestinal Epithelial Barrier Function [PDF]

Cells
At the intestinal front, several lines of defense are in place to resist infection and injury, the mucus layer, gut microbiome and strong epithelial junctions, to name a few. Their collaboration creates a resilient barrier.
Mariya Stepanova, Carol M. Aherne
doaj   +4 more sources

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coliSummary [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2017
Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
Ali Shawki, Declan F. McCole
doaj   +3 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier [PDF]

Advanced Science
Strict regulation of epithelial cells is crucial for maintaining intestinal barrier integrity and preventing intestinal diseases. While transcriptional regulation is well recognized as vital in this process, translational regulation is equally important.
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
doaj   +2 more sources

Baicalin mitigates hyperglycemia-linked intestinal epithelial barrier impairment in part by inhibiting the formation of neutrophil extracellular traps [PDF]

Frontiers in Immunology
BackgroundUnder hyperglycemic conditions, impaired intestinal barrier integrity leads to heightened level of inflammation, playing important roles in driving diabetic complications.
Yiqing Cai, Qinbo Yang, Qinbo Yang, Xinmiao Tang, Peiwei Wang, Peiwei Wang, Jingang Cui, Jingang Cui, Xiaoye Du, Xiaoye Du, Teng Zhang, Teng Zhang, Yu Chen, Yu Chen, Yu Chen   +14 more
doaj   +2 more sources

Deciphering the Complex Signaling Systems That Regulate Intestinal Epithelial Cell Death Processes and Shedding [PDF]

Frontiers in Immunology, 2017
Intestinal epithelial cells play a fundamental role in maintaining homeostasis. Shedding of intestinal cells in a controlled manner is critical to maintenance of barrier function.
Angela M. Patterson, Angela M. Patterson, Alastair J. M. Watson, Alastair J. M. Watson   +3 more
doaj   +4 more sources

Intestinal epithelial barrier and mucosal immunity

Cellular and Molecular Life Sciences, 2005
Intestinal mucosa integrates primary digestive functions with immune functions such as pathogen surveillance, antigen transport and induction of mucosal immunity and tolerance. Intestinal adaptive immunity is elicited in organized mucosa-associated lymphoid tissue (O-MALT) that is composed of antigen-presenting cells and lymphocytes and achieved by ...
J. Kunisawa, H. Kiyono
  +12 more sources

Editorial: Intestinal epithelial barrier disruption by enteric pathogens. [PDF]

Front Cell Infect Microbiol, 2023
Bhunia AK, Al-Sadi R.
europepmc   +4 more sources

Allicin Improves Intestinal Epithelial Barrier Function and Prevents LPS-Induced Barrier Damages of Intestinal Epithelial Cell Monolayers [PDF]

Frontiers in Immunology, 2022
Gut barrier disruption is the initial pathogenesis of various diseases. We previously reported that dietary allicin improves tight junction proteins in the endoplasmic reticulum stressed jejunum. However, whether the allicin benefits the gut barrier within mycotoxin or endotoxin exposure is unknown.
Jingxia Gao, Guanzhong Song, Haibo Shen, Yiming Wu, Chongqi Zhao, Zhuo Zhang, Qian Jiang, Qian Jiang, Xilong Li, Xiaokang Ma, Bie Tan, Yulong Yin, Yulong Yin   +12 more
openaire   +3 more sources

Role of Autophagy Inducers and Inhibitors in Intestinal Barrier Injury Induced by Intestinal Ischemia–Reperfusion (I/R)

Journal of Immunology Research, 2022
Objectives. Intestinal epithelial barrier function is an important mechanical barrier to maintain intestinal homeostasis and resist the invasion of intestinal pathogens and microorganisms.
Yuejin Li, Peng Zhang, Jian Zhang, Weimin Bao, Jinyuan Li, Yan Wei, Jinchao Ni, Kunmei Gong   +7 more
doaj   +1 more source

Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis

Newborn, 2022
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal barrier is altered in NEC, which potentially contributes to its pathogenesis by promoting intestinal bacterial translocation and stimulating the inflammatory response.
Managlia, Elizabeth, Yan, Xiaocai, De Plaen, Isabelle G   +2 more
openaire   +2 more sources