Results 11 to 20 of about 201,161 (293)
Intestinal epithelial barrier and mucosal immunity
Cellular and Molecular Life Sciences, 2005 Intestinal mucosa integrates primary digestive functions with immune functions such as pathogen surveillance, antigen transport and induction of mucosal immunity and tolerance. Intestinal adaptive immunity is elicited in organized mucosa-associated lymphoid tissue (O-MALT) that is composed of antigen-presenting cells and lymphocytes and achieved by ...
M. Rumbo, E. J. Schiffrin
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Regulation of Oxygen Homeostasis at the Intestinal Epithelial Barrier Site [PDF]
International Journal of Molecular Sciences, 2021 The unique biology of the intestinal epithelial barrier is linked to a low baseline oxygen pressure (pO2), characterised by a high rate of metabolites circulating through the intestinal blood and the presence of a steep oxygen gradient across the epithelial surface.
Špela Konjar +2 more
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Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis
Newborn, 2022 Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal barrier is altered in NEC, which potentially contributes to its pathogenesis by promoting intestinal bacterial translocation and stimulating the inflammatory response.
Managlia, Elizabeth +2 more
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Contributions of intestinal epithelial barriers to health and disease [PDF]
Experimental Cell Research, 2017 A core function of epithelia is to form barriers that separate tissue compartments within complex organisms. These barriers also separate the internal milieu from the external environment and are, therefore, an essential component of host defense. However, in many cases, a perfect barrier would be improbable with life itself.
Wangsun, Choi +2 more
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Allicin Improves Intestinal Epithelial Barrier Function and Prevents LPS-Induced Barrier Damages of Intestinal Epithelial Cell Monolayers [PDF]
Frontiers in Immunology, 2022 Gut barrier disruption is the initial pathogenesis of various diseases. We previously reported that dietary allicin improves tight junction proteins in the endoplasmic reticulum stressed jejunum. However, whether the allicin benefits the gut barrier within mycotoxin or endotoxin exposure is unknown.
Jingxia Gao +12 more
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TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. [PDF]
PLoS ONE, 2011 Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and ...
Lauren E Kolodziej +11 more
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Age-Associated Remodeling of the Intestinal Epithelial Barrier [PDF]
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013 Disorders of the gastrointestinal tract are common in the elderly people; however, the precise trait(s) of aging that contribute to the vulnerability of the gastrointestinal tract are poorly understood. Recent evidence suggests that patients with gastrointestinal disorders have increased intestinal permeability.
Lee, Tran +1 more
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Microecology, intestinal epithelial barrier and necrotizing enterocolitis [PDF]
Pediatric Surgery International, 2009 Soon after birth, the neonatal intestine is confronted with a massive antigenic challenge of microbial colonization. Microbial signals are required for maturation of several physiological, anatomical, and biochemical functions of intestinal epithelial barrier (IEB) after birth.
Renu, Sharma, Joseph J, Tepas
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Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020 Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva +2 more
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Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. [PDF]
PLoS ONE, 2017 The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and intestinal secretions, prevents passage of luminal substances and antigens through the paracellular space.
Hui Yan, Kolapo M Ajuwon
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