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Intestinal epithelial barrier and mucosal immunity
Intestinal mucosa integrates primary digestive functions with immune functions such as pathogen surveillance, antigen transport and induction of mucosal immunity and tolerance. Intestinal adaptive immunity is elicited in organized mucosa-associated lymphoid tissue (O-MALT) that is composed of antigen-presenting cells and lymphocytes and achieved by ...
J. Kunisawa, H. Kiyono
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Allicin Improves Intestinal Epithelial Barrier Function and Prevents LPS-Induced Barrier Damages of Intestinal Epithelial Cell Monolayers [PDF]
Gut barrier disruption is the initial pathogenesis of various diseases. We previously reported that dietary allicin improves tight junction proteins in the endoplasmic reticulum stressed jejunum. However, whether the allicin benefits the gut barrier within mycotoxin or endotoxin exposure is unknown.
Jingxia Gao +12 more
openaire +3 more sources
Editorial: Intestinal epithelial barrier disruption by enteric pathogens. [PDF]
Bhunia AK, Al-Sadi R.
europepmc +4 more sources
Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal barrier is altered in NEC, which potentially contributes to its pathogenesis by promoting intestinal bacterial translocation and stimulating the inflammatory response.
Managlia, Elizabeth +2 more
openaire +2 more sources
Microecology, intestinal epithelial barrier and necrotizing enterocolitis [PDF]
Soon after birth, the neonatal intestine is confronted with a massive antigenic challenge of microbial colonization. Microbial signals are required for maturation of several physiological, anatomical, and biochemical functions of intestinal epithelial barrier (IEB) after birth.
Renu, Sharma, Joseph J, Tepas
openaire +2 more sources
A bioactive bovine whey protein extract improves intestinal barrier function in vitro
The human intestine plays an important role as a barrier against the ingress of pathogens and other harmful antigens. Accordingly, proper regulation of the intestinal barrier is essential for optimal health.
Dulantha Ulluwishewa +4 more
doaj +1 more source
Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva +2 more
doaj +1 more source
The intestinal epithelial barrier is carrying out two major functions: restricting the entry of potentially harmful substances while on the other hand allowing the selective passage of nutrients.
Katrin Sommer +9 more
doaj +1 more source
The intestinal epithelium provides an important barrier against bacterial endotoxin translocation, which can regulate the absorption of water and ions. The disruption of epithelial barrier function can result in water transport and tight junction damage,
Baoping Zhang +5 more
doaj +1 more source
Background Sepsis is a major cause of death in ICU, and intestinal barrier dysfunction is its important complication, while the treatment is limited. Recently, mesenchymal stem cell-derived microvesicles (MMVs) attract much attention as a strategy of ...
Danyang Zheng +7 more
doaj +1 more source

