Results 11 to 20 of about 196,268 (297)
The intestinal epithelial barrier: a therapeutic target? [PDF]
Nature Reviews Gastroenterology & Hepatology, 2016 A fundamental function of the intestinal epithelium is to act as a barrier that limits interactions between luminal contents such as the intestinal microbiota, the underlying immune system and the remainder of the body, while supporting vectorial transport of nutrients, water and waste products.
Matthew A, Odenwald, Jerrold R, Turner
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Microbiome, 2023 Background The intestinal epithelial barrier confers protection against the intestinal invasion by pathogens and exposure to food antigens and toxins. Growing studies have linked the gut microbiota to the intestinal epithelial barrier function.
Jun Hu +5 more
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Microecology, intestinal epithelial barrier and necrotizing enterocolitis [PDF]
Pediatric Surgery International, 2009 Soon after birth, the neonatal intestine is confronted with a massive antigenic challenge of microbial colonization. Microbial signals are required for maturation of several physiological, anatomical, and biochemical functions of intestinal epithelial barrier (IEB) after birth.
Renu, Sharma, Joseph J, Tepas
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Human organoids are superior to cell culture models for intestinal barrier research
Frontiers in Cell and Developmental Biology, 2023 Loss of intestinal epithelial barrier function is a hallmark in digestive tract inflammation. The detailed mechanisms remain unclear due to the lack of suitable cell-based models in barrier research.
Catherine Kollmann +10 more
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Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage [PDF]
, 2015 Aminosalicylates, corticosteroids and immunosuppressants are currently the therapeutic choices in inflammatory bowel diseases (IBD), however, with limited remission and often serious side effects.
Brun, Paola +10 more
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TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. [PDF]
PLoS ONE, 2011 Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and ...
Lauren E Kolodziej +11 more
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Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. [PDF]
PLoS ONE, 2017 The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and intestinal secretions, prevents passage of luminal substances and antigens through the paracellular space.
Hui Yan, Kolapo M Ajuwon
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A bioactive bovine whey protein extract improves intestinal barrier function in vitro
JDS Communications, 2022 The human intestine plays an important role as a barrier against the ingress of pathogens and other harmful antigens. Accordingly, proper regulation of the intestinal barrier is essential for optimal health.
Dulantha Ulluwishewa +4 more
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Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020 Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva +2 more
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Frontiers in Medicine, 2021 The intestinal epithelial barrier is carrying out two major functions: restricting the entry of potentially harmful substances while on the other hand allowing the selective passage of nutrients.
Katrin Sommer +9 more
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