Results 271 to 280 of about 196,559 (297)

Ethanol modulation of intestinal epithelial tight junction barrier

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1999
Previous studies have shown that high concentrations of ethanol (≥40%) cause functional damage of the gastrointestinal epithelial barrier by direct cytotoxic effect on the epithelial cells. The effects of lower noncytotoxic doses of ethanol on epithelial barrier function are unknown.
T Y, Ma, D, Nguyen, V, Bui, H, Nguyen, N, Hoa   +4 more
openaire   +2 more sources

Antibody‐Mediated Antigen Sampling across Intestinal Epithelial Barriers

Annals of the New York Academy of Sciences, 2006
Abstract:  The epithelium of the gastrointestinal tract is the interface between luminal contents and the mucosal immune system. It must function as a selective barrier to limit penetration of antigens yet keep the mucosal immune system “informed” for the purpose of generating oral tolerance responses to food antigens or commensal organisms and host ...
M Cecilia, Berin, Hongxing, Li, Kirk, Sperber   +2 more
openaire   +2 more sources

Glutamine Blocks Interleukin-13-Induced Intestinal Epithelial Barrier Dysfunction

Digestion, 2019
Introduction: Impaired intestinal epithelial barrier function is a hallmark of a variety of pathological conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). IBD patients with IBS-like symptoms show higher interleukin-13 (IL-13) serum levels and poor psychological well-being.
Min Li, Tadayuki Oshima, Chiyomi Ito, Mayumi Yamada, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa   +6 more
openaire   +2 more sources

Innate defenses of the intestinal epithelial barrier.

Cellular and molecular life sciences : CMLS, 2005
The innate immune system plays a crucial role in maintaining the integrity of the intestine and protecting the host against a vast number of potential microbial pathogens from resident and transient gut microflora. Mucosal epithelial cells and Paneth cells produce a variety of antimicrobial peptides (defensins, cathelicidins, crytdinrelated sequence ...
C A, Müller, I B, Autenrieth, A, Peschel   +2 more
openaire   +1 more source

The blood–tumour barrier in cancer biology and therapy

Nature Reviews Clinical Oncology, 2021
Patricia S Steeg
exaly  

Impact of enteric bacterial infections at and beyond the epithelial barrier

Nature Reviews Microbiology, 2022
Ashleigh P Rogers, Steven J Mileto, Dena Lyras   +2 more
exaly  

Strategies for delivering therapeutics across the blood–brain barrier

Nature Reviews Drug Discovery, 2021
Georg C Terstappen, Wandong Zhang
exaly  

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

Nature Reviews Immunology, 2021
Cezmi A Akdis
exaly  

The nature of the intestinal epithelial barrier

The American Journal of Digestive Diseases, 1971
openaire   +2 more sources

The blood–brain barrier: Structure, regulation and drug delivery

Signal Transduction and Targeted Therapy, 2023
Di Wu, Qi Chen
exaly