Results 151 to 160 of about 670,112 (215)

Bacillus Licheniformis‐Induced Cognitive Decline in Mice Linking Gut Microbiota Dysbiosis, Metabolic Perturbations, and Hippocampal Neuroinflammation

Advanced Science, EarlyView.
Chronic oral administration of specific probiotic strains triggers gut microbiota dysbiosis and systemic metabolic perturbations in mice. Multi‐omics profiling reveals subsequent hippocampal glial remodeling and neuroinflammation, which are linked to cognitive impairment.
Yibin Lin, Afeng Wang, Hongchang Zhou, Yuliang Sun, Yingying Guo, Keyu Chen, Junhong Sun, Tinliang Lin, Zhaochen Huang, Xinhua Qiang, Jie He, Jianlin Lou, Yunliang Yao, Shengwen Shao, Yongliang Pan, Xiang Wang   +15 more
wiley   +1 more source

Allium sativum, a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi, Bright E. Igere, Anthony J. Anozie, Oghenenyore A. Ohwokevwo   +3 more
wiley   +1 more source

Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama, Haruhiko Cho, Takaki Yoshikawa   +2 more
wiley   +1 more source

The Role of Gut Microbiota on Intestinal Fibrosis in Inflammatory Bowel Disease and Traditional Chinese Medicine Intervention [PDF]

Leyao Fang,1– 3 Huiyi Peng,1– 3 Zhoujin Tan,2,3 Na Deng,2,3 Xinxin Peng1,2 1The First Hospital of Hunan University of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, People’s Republic of China; 2The Domestic First-Class Discipline ...
Peng H, Peng X, Deng N, Tan Z, Fang L
core  

Age‐Specific Temporal Trends and Climate‐Associated Seasonality of Appendectomy in Japan: A Nationwide Population‐Based Study Using the National Database

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim This study investigated nationwide temporal trends, age‐specific changes, and seasonal variations in appendectomies in Japan using the national database of health insurance claims and specific health checkups (NDB). Methods Data on appendectomies (open [OA] and laparoscopic [LA]) were extracted from the 2018–2023 NDB Open Data.
Shutaro Sumiyoshi, Masamitsu Kido, Tomohiro Arita, Naosuke Nakamichi, Kento Kurashima, Kenji Nanishi, Jun Kiuchi, Hiroki Shimizu, Kengo Yoshii, Atsushi Shiozaki   +9 more
wiley   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

La microbiota intestinal com a òrgan: impacte en fisiologia i patologia

, 2012
Microbiota intestinal; Fisiologia i patologia; ÒrganMicrobiota intestinal; Fisiología y patología; ÓrganoIntestinal microbiota; Physiology and pathology; OrganComunicació sobre l'impacte en fisiologia i patologia de la microbiota intestinal com a ...
Guarner Aguilar, Francisco
core  

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

Animal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud, Aysar Nashef, Imad Abu‐Elnaaj, Fuad A. Iraqi   +3 more
wiley   +1 more source

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source