Results 1 to 10 of about 995,413 (370)

Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms. [PDF]

Proc Natl Acad Sci U S A, 2012
Studies of tumors from human familial adenomatous polyposis, sporadic colon cancer, and mouse and rat models of intestinal cancer indicate that the majority of early adenomas develop through loss of normal function of the Adenomatous polyposis coli ( APC ) gene.
Amos-Landgraf JM, Irving AA, Hartman C, Hunter A, Laube B, Chen X, Clipson L, Newton MA, Dove WF.   +8 more
europepmc   +7 more sources

Retrospective analysis of the Zebrafish International Resource Center diagnostic data links Pseudocapillaria tomentosa to intestinal neoplasms in zebrafish Danio rerio (Hamilton 1822). [PDF]

J Fish Dis, 2020
The zebrafish has now emerged as a very important model in biomedical research, second only to the mouse (Völkel, Dupret, Le Bourhis, & Angrand, 2018).
Schaaf RM, Sharpton TJ, Murray KN, Kent AD, Kent ML.   +4 more
europepmc   +4 more sources

Association between intestinal neoplasms and celiac disease: A review. [PDF]

World J Gastrointest Oncol, 2021
Celiac disease (CD) is a chronic immune-mediated intestinal disease with genetic susceptibility. It is characterized by inflammatory damage to the small intestine after ingestion of cereals and products containing gluten protein. In recent years, the global prevalence rate of CD has been approximately 1%, and is gradually increasing. CD patients adhere
Wang M, Yu M, Kong WJ, Cui M, Gao F.
europepmc   +5 more sources

Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms. [PDF]

Int J Cancer, 2017
Morris SM, Davison J, Carter KT, O'Leary RM, Trobridge P, Knoblaugh SE, Myeroff LL, Markowitz SD, Brett BT, Scheetz TE, Dupuy AJ, Starr TK, Grady WM.   +12 more
europepmc   +4 more sources

Low-grade mucinous neoplasm originating from intestinal duplication: a case report and review of the literature [PDF]

World Journal of Surgical Oncology
Background Low-grade mucinous neoplasms typically originate from the appendix and are characterized by a lining of low-grade mucus-secreting columnar epithelial cells and smooth muscle.
Huihui Yin, Jie Yu, Yunzhao Chen
doaj   +3 more sources

Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-DOTATATE; Differences in Tumor Dosimetry, Vascularity and Lesion Metrics in Pancreatic and Small Intestinal Neuroendocrine Neoplasms [PDF]

Cancers, 2021
Simple Summary Patients suffering from disseminated, progressive, neuroendocrine neoplasms with a sufficient amount of somatostatin receptors and good kidney function can be treated with radioactive hormone-like molecules to prolong their life.
Ulrika Jahn, Ezgi Ilan, Mattias Sandström, Mark Lubberink, Ulrike Garske‐Román, Anders Sundin   +5 more
openalex   +2 more sources

Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice. [PDF]

J Exp Med, 2014
The development of serrated polyps in the cecum is driven by the interplay among genetic changes in the host, an inflammatory response, and a host-specific microbiota.
Bongers G, Pacer ME, Geraldino TH, Chen L, He Z, Hashimoto D, Furtado GC, Ochando J, Kelley KA, Clemente JC, Merad M, van Bakel H, Lira SA.   +12 more
europepmc   +2 more sources

Multiple intestinal hemangioma concurrent with low-grade appendiceal mucinous neoplasm presenting as intussusception—a case report and literature review [PDF]

World Journal of Surgical Oncology, 2022
Background Cases with intussusception caused by either intestinal hemangiomas or appendiceal mucinous neoplasms are extremely rare. Case presentation In this study, we reported a 47-year-old male presented with paroxysmal abdominal pain and postprandial ...
Yanhua Yang, Dongmei Jia, Chen Jiang
doaj   +2 more sources

Pathogenesis and Clinical Management of Mesenteric Fibrosis in Small Intestinal Neuroendocine Neoplasms: A Systematic Review [PDF]

Journal of Clinical Medicine, 2020
Mesenteric fibrosis (MF) constitutes an underrecognized sequela in patients with small intestinal neuroendocrine neoplasms (SI-NENs), often complicating the disease clinical course.
Anna Koumarianou, Krystallenia Alexandraki, Göran Wallin, Gregory Kaltsas, Kosmas Daskalakis   +4 more
openalex   +2 more sources

TGF-β Receptor Inactivation and Mutant Kras Induce Intestinal Neoplasms in Mice via a β-Catenin-Independent Pathway [PDF]

Gastroenterology, 2009
BACKGROUND & AIMS During colorectal cancer pathogenesis, mutations and epigenetic events cause neoplastic behavior in epithelial cells by deregulating the Wnt, Ras-Raf-extracellular signal-regulated kinase (ERK), and transforming growth factor (TGF)-beta-
Patty Trobridge, Sue E. Knoblaugh, M. Kay Washington, Nina M. Muñoz, Karen D. Tsuchiya, Andrés Rojas, Xiaoling Song, Cornelia M. Ulrich, Takehiko Sasazuki, Senji Shirasawa, William M. Grady   +10 more
openalex   +2 more sources