Results 31 to 40 of about 618,612 (300)

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Multiple intestinal hemangioma concurrent with low-grade appendiceal mucinous neoplasm presenting as intussusception—a case report and literature review

World Journal of Surgical Oncology, 2022
Background Cases with intussusception caused by either intestinal hemangiomas or appendiceal mucinous neoplasms are extremely rare. Case presentation In this study, we reported a 47-year-old male presented with paroxysmal abdominal pain and postprandial ...
Yanhua Yang, Dongmei Jia, Chen Jiang
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

An Intestinal Lipoma Presenting as a Case of Intussusception [PDF]

International Journal of Anatomy Radiology and Surgery, 2017
Intussusception is a process of invagination of proximal bowel into distal part. Although, most of the cases in children are idiopathic. Neoplasms (benign or malignant) are the most common causes reported in the adults.
Ipsita Acharya, Sanjib Das
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Uncommon Presentations of Pancreatic Neoplasms, Rare Neoplasms, and Peripancreatic Masses

, 2022
Pancreatic masses with atypical radiological appearance are frequently encountered. Atypical presentation of common pancreatic tumor is also possible.
Antonia Olivieri, Roberto Calbi, Paola Capelli, Angela Calabrese, Paolo Tinazzi Martini, Nicolò Cardobi, Mirko D’Onofrio, Riccardo De Robertis, Luca Geraci   +8 more
core   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Travis, W., Linehan, M., Karl, M., Chrousos, G. P., Allolio, B., Mastorakis, G., Reincke, Martin   +6 more
core   +1 more source

COLOCOLIC INTUSSUSCEPTION ASSOCIATED WITH INTESTINAL LEIOMYOSARCOMA IN A DOG

Slovenian Veterinary Research
A 7-year-old neutered Standard Poodle was admitted due to chronic bloody diarrhea. The owner reported that the symptoms began approximately 5 months prior, including diarrhea, hyporexia, tenesmus, and weight loss. After performing a clinical examination,
Andres Julian Ospina Sáenz, Ricardo Andrés Correa   +1 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source