Results 51 to 60 of about 618,612 (300)

Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice.

PLoS ONE, 2014
Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasms (IPMNs).
Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi, Yuko Goto, Taro Hara, Dai Ikebe, Taketo Yamaguchi, Yoshifumi Arisaka, Toru Niihara, Hiroto Nishimata, Sadao Tanaka, Kyoichi Takaori, Surinder K Batra, Suguru Yonezawa   +13 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Variants of gallbladder adenocarcinomas: Five case reports

Sahel Medical Journal, 2016
Conventional adenocarcinomas comprise of about 90% of all gallbladder neoplasms; among them, pancreatobiliary is the most common phenotype followed by intestinal and gastric foveolar types.
Subhajit Das, Debjit Banerjee, Soumit Mondal, Pankaj Tayal   +3 more
doaj   +1 more source

A Review of Colonoscopy in Intestinal Diseases

Diagnostics, 2023
Since the development of the fiberoptic colonoscope in the late 1960s, colonoscopy has been a useful tool to diagnose and treat various intestinal diseases.
Seung Min Hong, Dong Hoon Baek
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Identification of a new intestinal spirochete with pathogenicity for chickens [PDF]

, 1995
Two intestinal spirochete isolates obtained from chickens with diarrhea were examined by electron microscopy, biochemical tests, rRNA gene restriction pattern analysis, and multilocus enzyme electrophoresis.
Hampson, D.J., Jensen, N.S., Swayne, D.E, Stoutenburg, J., Trott, D.J., Eaton, K.A.   +5 more
core  

Add-on to current guidelines for monitoring of SBS patients treated with teduglutide

npj Gut and Liver
By inducing growth of the intestinal epithelium, the drug teduglutide, used for the treatment of short bowel syndrome-associated intestinal failure, could feasibly promote growth of pre-existing colonic neoplasms and incite the development of new ones. A
Francisca Joly, Johane P. Allard, Gabriel E. Gondolesi, Palle Bekker Jeppesen, Martina Kohl-Sobania, Ulrich-Frank Pape, Loris Pironi, Lauren K. Schwartz, Joel Mason   +8 more
doaj   +1 more source

Solitary plasmacytoma extramedullary to duodenal level: an unusual case of intestinal occlusion

Galicia Clínica, 2019
Plasma cell neoplasms represent only 1-2% of hematological malignancies and intestinal plasmocytoma represents only 3%. Extramedullary plasmocytomas most commonly are located in upper airway and oral cavity; the gastrointestinal plasmocytoma only ...
Manuel Lorenzo López Reboiro, Inés Navarro Menéndez, Lucía Cid Conde, José López Castro   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Verstegen, M.W.A., Metzler-Zebeli, B.U., Mosenthin, R.   +3 more
core   +1 more source