Results 61 to 70 of about 1,183,535 (296)

Familial adenomatous polyposis coli

Journal of the Belgian Society of Radiology, 2011
Background: A 53-year-old male patient with a familial history of colon carcinoma presented with stool changes and abdominal cramps. There was no weight loss nor signs of blood in the stool.
K Boeren, Y Vankan, D Perdieus
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice.

PLoS ONE, 2014
Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasms (IPMNs).
Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi, Yuko Goto, Taro Hara, Dai Ikebe, Taketo Yamaguchi, Yoshifumi Arisaka, Toru Niihara, Hiroto Nishimata, Sadao Tanaka, Kyoichi Takaori, Surinder K Batra, Suguru Yonezawa   +13 more
doaj   +1 more source

Leiomyoma of ileum causing intestinal obstruction: A rare presentation

Saudi Journal for Health Sciences, 2021
Leiomyoma is a benign mesenchymal neoplasms arising from smooth muscles which accounts for 20%–30% of all benign gastrointestinal tumours. The occurrence of leiomyoma in ileum is rare.
Abhay Vilas Deshmukh, Vihanka Devchand Vaidya, Vitaladevuni Balasubramanyam Shivkumar, Nitin M Gangane   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Variants of gallbladder adenocarcinomas: Five case reports

Sahel Medical Journal, 2016
Conventional adenocarcinomas comprise of about 90% of all gallbladder neoplasms; among them, pancreatobiliary is the most common phenotype followed by intestinal and gastric foveolar types.
Subhajit Das, Debjit Banerjee, Soumit Mondal, Pankaj Tayal   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Add-on to current guidelines for monitoring of SBS patients treated with teduglutide

npj Gut and Liver
By inducing growth of the intestinal epithelium, the drug teduglutide, used for the treatment of short bowel syndrome-associated intestinal failure, could feasibly promote growth of pre-existing colonic neoplasms and incite the development of new ones. A
Francisca Joly, Johane P. Allard, Gabriel E. Gondolesi, Palle Bekker Jeppesen, Martina Kohl-Sobania, Ulrich-Frank Pape, Loris Pironi, Lauren K. Schwartz, Joel Mason   +8 more
doaj   +1 more source

Solitary plasmacytoma extramedullary to duodenal level: an unusual case of intestinal occlusion

Galicia Clínica, 2019
Plasma cell neoplasms represent only 1-2% of hematological malignancies and intestinal plasmocytoma represents only 3%. Extramedullary plasmocytomas most commonly are located in upper airway and oral cavity; the gastrointestinal plasmocytoma only ...
Manuel Lorenzo López Reboiro, Inés Navarro Menéndez, Lucía Cid Conde, José López Castro   +3 more
doaj   +1 more source