Results 21 to 30 of about 49,154 (113)

Effects of Fructus Psoraleae Extract on the Intestinal Absorption Kinetics of Geniposide and Geniposidic Acid in Rat

Molecules, 2014
Cortex Eucommia has been used as a kidney-tonifying herbal medicine with a long history of compatibility with Fructus Psoraleae. Geniposide (GP) and geniposidic acid (GPA) are the two main chemical components in Cortex Eucommia. In the present study, the
Yan Huo, Yuxing Huang, Xiangmei Hou, Lifeng Han, Lei Wang, Erwei Liu, Xiumei Gao   +6 more
doaj   +1 more source

Regulatory Effect of Lactiplantibacillus plantarum 2-33 on Intestinal Microbiota of Mice With Antibiotic-Associated Diarrhea

Frontiers in Nutrition, 2022
Diarrhea is one of the common adverse reactions in antibiotic treatment, which is usually caused by the imbalance of intestinal flora, and probiotics play an important role in the structure of intestinal flora.
Wuyundalai Bao, Yuxing He, Jinghe Yu, Mingchao Liu, Xiaofeng Yang, Na Ta, Enxin Zhang, Chengyuan Liang   +7 more
doaj   +1 more source

Openable artificial intestinal tract device integrated with a permeable filter for evaluating drug permeation through cells

Scientific Reports, 2023
Organs-on-chips using cultured cells have been developed and applied for evaluating in vitro biological phenomena. We previously reported an openable artificial intestinal tract system, as an in vitro model of the small intestine, for in vitro drug ...
Satoshi Konishi, Shingo Ishibashi, Shiho Shimizu, Keita Watanabe, Rodi Abdalkader, Takuya Fujita   +5 more
doaj   +1 more source

Hyperspectral imaging detects perfusion and oxygenation differences between stapled and hand-sewn intestinal anastomoses

Innovative Surgical Sciences, 2022
Hand-sewn and stapled intestinal anastomoses are both daily performed routine procedures by surgeons. Yet, differences in micro perfusion of these two surgical techniques and their impact on surgical outcomes are still insufficiently understood.
Wagner Tristan, Radunz Sonia, Becker Felix, Chalopin Claire, Kohler Hannes, Gockel Ines, Jansen-Winkeln Boris   +6 more
doaj   +1 more source

IFABP and TFF3 as predictors for intestinal health in the perioperative setting in children with congenital heart disease

Frontiers in Cardiovascular Medicine
IntroductionChildren with congenital heart disease (CHD) undergoing cardiac surgery are at heightened risk of gastrointestinal complications due to imbalances in systemic and pulmonary blood flow, often resulting in impaired intestinal perfusion and ...
Nicolas Boerter, Noa Judith Freudenthal, Soyhan Bagci, Tobias Kratz, Johannes Breuer, Nicole Mueller   +5 more
doaj   +1 more source

Evaluating cell viability, capillary perfusion, and collateral tortuosity in an ex vivo mouse intestine fluidics model

Frontiers in Bioengineering and Biotechnology, 2022
Numerous disease conditions involve the sudden or progressive loss of blood flow. Perfusion restoration is vital for returning affected organs to full health.
Caroline E. Willi, Caroline E. Willi, Hanaa Abdelazim, Hanaa Abdelazim, John C. Chappell, John C. Chappell, John C. Chappell, John C. Chappell   +7 more
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Absorption and Transport of Sea Cucumber Saponins from Apostichopus japonicus

Marine Drugs, 2016
The present study is focused on the intestinal absorption of sea cucumber saponins. We determined the pharmacokinetic characteristics and bioavailability of Echinoside A and Holotoxin A1; the findings indicated that the bioavailability of Holotoxin A1 ...
Shuai Li, Yuanhong Wang, Tingfu Jiang, Han Wang, Shuang Yang, Zhihua Lv   +5 more
doaj   +1 more source

Evaluation of the NMR-MOUSE as a new method for continuous functional monitoring of the small intestine during different perfusion states in a porcine model. [PDF]

PLoS ONE, 2018
OBJECTIVE:The study aim was to evaluate a small low-field NMR (nuclear magnetic resonance) scanner, the NMR-MOUSE®, for detecting changes in intestinal diffusion under different (patho-) physiological perfusion states. METHODS:Laparotomy was performed on
Paula R Keschenau, Hanna Klingel, Silke Reuter, Ann Christina Foldenauer, Jochen Vieß, Dennis Weidener, Julia Andruszkow, Bernhard Bluemich, René Tolba, Michael J Jacobs, Johannes Kalder   +10 more
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Bilosomes and Niosomes for Enhanced Intestinal Absorption and In Vivo Efficacy of Cytarabine in Treatment of Acute Myeloid Leukemia

Pharmaceuticals
Cytarabine (CTR) is a hydrophilic anticancer drug used to treat leukemia. It suffers from poor permeability and intestinal metabolism, diminishing its oral bioavailability.
Abdelrahman R. Said, Mona F. Arafa, Walaa A. El-Dakroury, Sultan Alshehri, Gamal M. El Maghraby   +4 more
doaj   +1 more source

The Preventive Effects of Probiotic Prevotella histicola on the Bone Loss of Mice with Ovariectomy-Mediated Osteoporosis

Microorganisms, 2023
It has been demonstrated that the disturbance of gut microbiota (GM) is closely related to the reduction of bone mass and incidence of osteoporosis (OP). The aim of this study is to investigate whether the supplementation of Prevotella histicola (Ph) can
Yuan-Wei Zhang, Mu-Min Cao, Ying-Juan Li, Ren-Wang Sheng, Ruo-Lan Zhang, Meng-Ting Wu, Jia-Yu Chi, Rui-Xin Zhou, Yun-Feng Rui   +8 more
doaj   +1 more source