Results 31 to 40 of about 49,154 (113)

Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury

Frontiers in Physiology, 2017
Background: Butyrate protects against ischemic injury to the small intestine by reducing inflammation and maintaining the structure of the intestinal barrier, but is expensive, short-lived, and cannot be administered easily due to its odor. Lactate, both
Alessandra Bertacco, Alessandra Bertacco, Carina A. Dehner, Carina A. Dehner, Giorgio Caturegli, Francesco D'Amico, Francesco D'Amico, Raffaella Morotti, Manuel I. Rodriguez, David C. Mulligan, Martin A. Kriegel, John P. Geibel   +11 more
doaj   +1 more source

Intestinal absorption and metabolism of 9-cis-beta-carotene in vivo: biosynthesis of 9-cis-retinoic acid.

Journal of Lipid Research, 1995
This study was done to examine the intestinal absorption and cleavage of 9-cis-beta-carotene in vivo. A micellar solution, containing either no addition or 10 mumol of 9-cis- or all-trans-beta-carotene, was perfused for 2 h through the upper portion of ...
X. Hébuterne, X.D. Wang, E.J. Johnson, N.I. Krinsky, R.M. Russell   +4 more
doaj   +1 more source

Correlation of minimally invasive imaging techniques to assess intestinal mucosal perfusion with established markers of chronic inflammatory enteropathy in dogs

Journal of Veterinary Internal Medicine, 2021
Background Minimally invasive diagnostic imaging techniques to detect intestinal inflammation in dogs are lacking. Contrast‐enhanced ultrasound (CEUS) and endoscopic narrow band imaging‐like endoscopy (Storz Professional Image Enhancement System [SPIES])
Mazdak Salavati, Jorge Pérez‐Accino, Yi Lin Tan, Tiziana Liuti, Sionagh Smith, Linda Morrison, Silke Salavati Schmitz   +6 more
doaj   +1 more source

Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model

Intensive Care Medicine Experimental, 2022
Background Interventions, such as mechanical ventilation with high positive end-expiratory pressure (PEEP), increase inflammation in abdominal organs.
Silvia Marchesi, Anders Larsson, Göran Hedenstierna, Mohammed Abujazar, Håkan Ahlström, Miklós Lipcsey   +5 more
doaj   +1 more source

Effects of Combined Live Bifidobacterium, Lactobacillus, Enterococcus, and Bacillus Cereus Tablets on the Structure and Function of the Intestinal Flora in Rabbits Undergoing Hepatic Artery Infusion Chemotherapy

Biology
Few studies have explored the biological mechanism by which probiotics alleviate adverse reactions to chemotherapy drugs after local hepatic chemotherapy perfusion by regulating the intestinal flora.
Xiangdong Yan, Liuhui Bai, Jin Lv, Ping Qi, Xiaojing Song, Lei Zhang   +5 more
doaj   +1 more source

In Situ Intestinal Perfusion of Irinotecan: Application to P-gp Mediated Drug Interaction and Introduction of an Improved HPLC Assay

Journal of Pharmacy & Pharmaceutical Sciences, 2011
PURPOSE: To determine experimentally the intestinal permeability of the anticancer prodrug irinotecan, and to quantify the amount of its cytotoxic metabolite SN-38 that is intestinally excreted (exsorped) as a predictor of intestinal toxicity, and to ...
Abdullah Khalil Rabba, Luqin Si, Kewen Xue, Ming Li, Gao Li   +4 more
doaj   +1 more source

Perfusion System for Modification of Luminal Contents of Human Intestinal Organoids and Realtime Imaging Analysis of Microbial Populations

Micromachines, 2022
Intestinal organoids are 3D cell structures that replicate some aspects of organ function and are organized with a polarized epithelium facing a central lumen.
Nicholas J. Ginga, Raleigh Slyman, Ge-Ah Kim, Eric Parigoris, Sha Huang, Veda K. Yadagiri, Vincent B. Young, Jason R. Spence, Shuichi Takayama   +8 more
doaj   +1 more source

TAURINE AND CAFFEINE-CONTAINING ENERGY DRINKS: LUMINAL PRESENCE OF TAURINE REDUCES BACLOFEN INTESTINAL ABSORPTION IN RATS [PDF]

Kafrelsheikh Veterinary Medical Journal, 2004
The absorption of baclofen (BAC), a centrally acting antispastic agent with γ-amino acid structure as well as the influence of taurine (TAU) and caffeine (CAFF) on baclofen permeability was investigated by in-situ single-pass rat intestinal perfusion ...
H. Spahn-Langguth, A. Hanafy, C. Leisen
doaj   +1 more source

The effects of lipopolysaccharide-induced endotoxic shock on the intestinal microcirculatory perfusion: an experimental study in pigs

Intensive Care Medicine Experimental
Background Impairment of microcirculatory tissue perfusion is a central element of sepsis. Unfortunately, monitoring microcirculatory tissue perfusion to detect microcirculatory dysfunction at the bedside remains challenging.
Moritz Flick, Brennan Schneider, Feras Hatib, Zhongping Jian, Bernd Saugel, Manuel Ignacio Monge García, Thomas W. L. Scheeren   +6 more
doaj   +1 more source

Evaluation of the Small Intestinal Functions Using the Extracorporeal Small Intestinal Serosa Voltage Measurement Method

IEEE Access
A rapid and non-invasive assessment method for small intestinal functions before organ transplantation has not yet been established. Machine perfusion is a novel organ preservation strategy and a promising technique that can maintain, restore, and ...
Satoshi Muto, Hiromichi Obara, Mio Takashima, Daisuke Ishii, Seisuke Sakamoto, Naoto Matsuno   +5 more
doaj   +1 more source