Results 91 to 100 of about 402,657 (223)

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]

, 2005
Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...
Denis E. Corpet, Pierre, Fabrice, Pierre, Fabrice H.F., Fabrice Pierre, Corpet, Denis E.   +4 more
core   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Hamartomatous polyposis syndromes: A review [PDF]

, 2014
Hamartomatous Polyposis Syndromes (HPS) are genetic syndromes, which include Peutz-Jeghers syndrome, Juvenile polyposis syndrome, PTEN hamartoma tumour syndrome (Cowden Syndrom, Bannayan-Riley-Ruvalcaba and Proteus Syndrome) as well as hereditary mixed ...
Nielsen, Claus Buhl, Hansen, Tine Plato, Tine Hansen, Lilian Ousager, Ousager, Lilian Bomme, Jelsig, Anne Marie, Brusgaard, Klaus, Anne Jelsig, Ousager, Lilian Bomme; id_orcid, Niels Qvist, Qvist, Niels, Klaus Brusgaard, Claus Nielsen   +12 more
core   +1 more source

Mantle cell lymphoma of the gastrointestinal tract presenting with multiple intussusceptions – case report and review of literature

World Journal of Surgical Oncology, 2009
Background Mantle cell lymphoma (MCL) is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. Extra nodal involvement is present in the majority of cases,
Abo Stephen M, Cosgrove John M, Reed Mary, Parikh Nalini S, Constantine Radu, Kella Venkata KN, King Saundra   +6 more
doaj   +1 more source

The classification of intestinal polyposis [PDF]

Nature Genetics, 2012
Peh Yean, Cheah, Kiat Hon, Lim, Poh Koon, Koh, Choong Leong, Tang   +3 more
openaire   +2 more sources

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms [PDF]

, 2011
BACKGROUND: While our knowledge of the intestinal microbiota during disease is accumulating, basic information of the microbiota in healthy subjects is still scarce.
Vos, W.M., de, Willem M de Vos, Immonen, Outi, Janne Nikkilä, de Vos Willem M., Jalanka-Tuovinen, J., Salonen Anne, Lahti Leo, Leo Lahti, Anne Salonen, Jalanka-Tuovinen, Jonna, de Vos, W.M., Airi Palva, Nikkilä Janne, Palva Airi, de Vos, Willem M., Immonen Outi, Kekkonen, Riina, Lahti, Leo, Palva, Airi, Kekkonen Riina, Nikkila, Janne, Jonna Jalanka-Tuovinen, Willem M. de Vos, Jalanka-Tuovinen Jonna, Riina Kekkonen, Outi Immonen, Salonen, Anne   +27 more
core   +1 more source

The Yin and Yang of Invariant Natural Killer T Cells in Tumor Immunity—Suppression of Tumor Immunity in the Intestine

Frontiers in Immunology, 2018
CD1d-restricted invariant natural killer T (iNKT) cells are known as early responding, potent regulatory cells of immune responses. Besides their established role in the regulation of inflammation and autoimmune disease, numerous studies have shown that ...
Ying Wang, Susanna L. Cardell
doaj   +1 more source

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open‐Source Artificial Intelligence Model SEE‐AI

DEN Open, Volume 7, Issue 1, April 2027.
AI‐assisted reading with the open‐source SEE‐AI model improves lesion detection sensitivity and reduces reading time in small‐bowel capsule endoscopy. In a multicenter retrospective study of 249 cases, SEE‐AI provides visual cues that support physicians during interpretation while preserving physician‐led final decisions.
Satoshi Miyazono, Junji Umeno, Tomohiro Nagasue, Takuto Saiki, Hisamitsu Kaku, Takehiro Torisu, Akihito Yokote, Keisuke Kawasaki, Yutaro Ihara, Yuichi Matsuno, Noriyuki Imazu, Tomohiko Moriyama, Ahmed Nashaat Mohamed, Katsuya Hirakawa, Hajime Yamagata, Yasuharu Okamoto, Koichi Kurahara, Shinichiro Yada, Akira Harada, Tetsuro Ago   +19 more
wiley   +1 more source