Results 81 to 90 of about 18,113 (219)

Leucine‐Restricted Diet Attenuates Small Intestinal Tumorigenesis in ApcMin/+ Mice

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Essential amino acids have been implicated in intestinal physiology and disease, but their individual roles in intestinal tumorigenesis remain unclear. Among the amino acids examined, dietary leucine restriction uniquely suppressed small intestinal tumorigenesis in ApcMin/+ mice.
Yunlong Sui, Namiko Hoshi, Norihiro Okamoto, Yuna Ku, Makoto Ooi, Daisuke Watanabe, Haruka Miyazaki, Misaki Agawa, Hirotaka Nakamura, Jun Inoue, Hui Yang, Yuzo Kodama   +11 more
wiley   +1 more source

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]

, 2005
Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...
Denis E. Corpet, Pierre, Fabrice, Pierre, Fabrice H.F., Fabrice Pierre, Corpet, Denis E.   +4 more
core   +1 more source

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Histopathology, Volume 89, Issue 1, Page 98-109, July 2026.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli, M. Elisa Vink‐Börger, Nanette S. van Roermund, Gesina van Lijnschoten, Chantal C.H.J. Kuijpers, Nicole C.T. van Grieken, Matteo Fassan, Joep E. Ijspeert, Rachel S. van der Post, Iris D. Nagtegaal   +9 more
wiley   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

Mantle cell lymphoma of the gastrointestinal tract presenting with multiple intussusceptions – case report and review of literature

World Journal of Surgical Oncology, 2009
Background Mantle cell lymphoma (MCL) is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. Extra nodal involvement is present in the majority of cases,
Abo Stephen M, Cosgrove John M, Reed Mary, Parikh Nalini S, Constantine Radu, Kella Venkata KN, King Saundra   +6 more
doaj   +1 more source

Intussusception reveals MUTYH-associated polyposis syndrome and colorectal cancer: a case report

BMC Cancer, 2019
Background We are reporting a rare case of MUTYH-associated polyposis, a colorectal cancer hereditary syndrome, diagnosticated after an intussusception.
Gustavo Heluani Antunes de Mesquita, Bárbara Justo Carvalho, Kayo Augusto de Almeida Medeiros, Fernanda Nii, Diego Ramos Martines, Leonardo Zumerkorn Pipek, Yuri Justi Jardim, Daniel Reis Waisberg, Marcos Takeo Obara, Roberta Sitnik, Alberto Meyer, Cristóvão Luis Pitangueiras Mangueira   +11 more
doaj   +1 more source

Giant desmoid tumor of the abdominal wall in a patient with Gardner Syndrome

Journal of Coloproctology, 2012
Gardner syndrome (GS) is a rare entity characterized by a triad of familial colonic polyposis, multiple osteomas and soft tissue tumors, including desmoid tumor (DT).
Daniel Paulino Santana, Juliano Alves Figueiredo, Matheus Matta Machado Mafra Duque Estrada Meyer, Paula Mendonça Pimenta Ferreira, Guilherme Sousa Sarmento Valente, Marcos Wanderley Campos Reis   +5 more
doaj  

Gardner's Syndrome revisited:a clinical case and overview of the literature

, 2016
Gardner's syndrome (GS), a variant of familial adenomatous polyposis (FAP), remains a life-threatening condition of significant dental relevance. Clinicians can play an important role in the identification of this condition as the dental manifestations ...
Seehra, Jadbinder; id_orcid, Patel, Shruti, Bryant, Catherine   +2 more
core   +1 more source

A rare case of Gardner syndrome in an African adult male: A case report

Clinical Case Reports
Key Clinical Message Gardner's syndrome with the complete manifestation of colonic and extracolonic features is uncommon. Therefore, every clinician should view extracolonic features with a high index of suspicion.
Olusegun I. Olaopa, Adedamola A. Dada, Oluwafunmilayo Y. Soneye, Oluwadamilare Iyapo, Taofeek A. Akinniyi, Akinyele O. Adisa, Kehinde K. Kanmodi, Adedolapo O. Olaopa, Christian I. Emeka, Imudia D. Ehanire, Modupe O. Coker   +10 more
doaj   +1 more source

Gentle Giant? Giant Gastric Solitary Peutz-Jeghers Polyp

: Solitary hamartomatous polyps with identical pathological features of the typical hamartomas of the Peutz-Jegher syndrome are extremely rare. These solitary lesions lack the associated intestinal polyposis, classic mucocutaneous pigmentation, and ...
Fuschillo, G, Nazzaro, L., Lauro, A, Fuschillo, G., Mongardini, F. M., Docimo, L., Mongardini, F M, Gambardella, C., Lauro, A., Landolfi, V., Gambardella, C, Landolfi, V, Nazzaro, L, D'Alelio, A, D’Alelio, A., Docimo, L   +15 more
core   +1 more source