Results 71 to 80 of about 402,657 (223)
FlexMat, EarlyView.Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue +5 more
wiley +1 more source
The importance of the dental examination in the primary diagnosis of Gardner′s syndrome
Journal of Oral and Maxillofacial Radiology, 2015 Gardner′s syndrome (GS) is an autosomal dominant, well-documented disease with characteristic systemic and maxillofacial manifestations. The diagnosis of GS is established by the presence of simultaneous findings of intestinal or colorectal polyposis and
Ömür Dereci +3 more
doaj +1 more source
Head &Neck, EarlyView.ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent +15 more
wiley +1 more source
IL-33 activates tumor stroma to promote intestinal polyposis [PDF]
, 2015 Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by nonepithelial stromal cells.
T. T. Pizarro +12 more
core +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad +5 more
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Aspirin has been used to treat pain and fever for 120 years. Its uses expanded into treating arthritis and prevention of thrombotic events. Its anti‐cancer role emerged with observational studies in the 1980's and subsequent cancer review in those treated with aspirin in cardiovascular trials.
John Burn, D. Timothy Bishop
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman +18 more
wiley +1 more source
Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in Sweden
International Journal of Cancer, EarlyView.ABSTRACT Available epidemiological evidence shows that many cancers share familial risks, and this is increasingly confirmed by data on shared pathogenic germline gene variants between cancers. We decided to harness the world's largest resource on familial cancer to assess discordant familial risks for female breast (BC), prostate (PC), colorectal (CRC)
Frantisek Zitricky +5 more
wiley +1 more source
Peutz-Jeghers Syndrome: In Siblings with Palmer-Plantar Pigmentation
Journal of Indian Academy of Oral Medicine and Radiology, 2011 Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant disorder characterized by typical pigmented perioral maculesn pigmented spots in the oral mucosa and digits along with hamartomatous polyps in the gastrointestinal tract.
K V Suresh +2 more
doaj +1 more source