Results 51 to 60 of about 18,329 (193)

The Yin and Yang of Invariant Natural Killer T Cells in Tumor Immunity—Suppression of Tumor Immunity in the Intestine

Frontiers in Immunology, 2018
CD1d-restricted invariant natural killer T (iNKT) cells are known as early responding, potent regulatory cells of immune responses. Besides their established role in the regulation of inflammation and autoimmune disease, numerous studies have shown that ...
Ying Wang, Susanna L. Cardell
doaj   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Can innovation in endoscopic therapy alter clinical outcomes in patients with familial adenomatous polyposis?

Endoscopy International Open, 2021
Monique E. van Leerdam, Andrew Latchford
doaj   +1 more source

Self‐Directed Mikoto Simulator Training for Colonoscopy in Gastroenterology Trainees: An International Multicenter Randomized Trial

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Objectives Simulation‐based colonoscopy training may support early acquisition of insertion skills, but its clinical effect remains uncertain. We evaluated whether a self‐directed curriculum using the mikoto colonoscopy simulator improved insertion performance in gastroenterology trainees.
Daisuke Yamaguchi, Ryo Shimoda, Masashi Fujii, Tomohiko Richard Ohya, Han‐Mo Chiu, Naoyuki Tominaga, Hidenori Hidaka, Hiroharu Kawakubo, Yosuke Minoda, Kosuke Maehara, Hiroko Fukuda, Takuma Okamura, Kiwamu Tanaka, Masakuni Kobayashi, Tetsuhito Muranaka, Shuichi Miyamoto, Mitsuru Esaki, Ayako Takamori, Yuichiro Ikebuchi, Taro Akashi, Naoyuki Yamaguchi, Masaru Ueki, Hajime Isomoto, Motohiro Esaki   +23 more
wiley   +1 more source

Peutz-Jeghers Syndrome: In Siblings with Palmer-Plantar Pigmentation

Journal of Indian Academy of Oral Medicine and Radiology, 2011
Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant disorder characterized by typical pigmented perioral maculesn pigmented spots in the oral mucosa and digits along with hamartomatous polyps in the gastrointestinal tract.
K V Suresh, Prashanth Shenai, Laxmikanth Chatra   +2 more
doaj   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open‐Source Artificial Intelligence Model SEE‐AI

DEN Open, Volume 7, Issue 1, April 2027.
AI‐assisted reading with the open‐source SEE‐AI model improves lesion detection sensitivity and reduces reading time in small‐bowel capsule endoscopy. In a multicenter retrospective study of 249 cases, SEE‐AI provides visual cues that support physicians during interpretation while preserving physician‐led final decisions.
Satoshi Miyazono, Junji Umeno, Tomohiro Nagasue, Takuto Saiki, Hisamitsu Kaku, Takehiro Torisu, Akihito Yokote, Keisuke Kawasaki, Yutaro Ihara, Yuichi Matsuno, Noriyuki Imazu, Tomohiko Moriyama, Ahmed Nashaat Mohamed, Katsuya Hirakawa, Hajime Yamagata, Yasuharu Okamoto, Koichi Kurahara, Shinichiro Yada, Akira Harada, Tetsuro Ago   +19 more
wiley   +1 more source

Reexamining Multisystem Desmoid Tumors Linked to Gardner’s Syndrome: A Clinical Case

Case Reports in Gastrointestinal Medicine
A variation of familial adenomatous polyposis (FAP), known as Gardner’s syndrome (GS), can manifest as extraintestinal tumors, such as desmoid tumors (DTs). A key part in the diagnosing process is played by the clinician.
Haijia Zhang, Yongjie Wu, Xiushan Dong, Jie An   +3 more
doaj   +1 more source

Computed tomography findings of diffuse gastrointestinal mantle cell lymphoma

Radiology Case Reports, 2017
Multiple lymphomatous polyposis is an uncommon type of primary non-Hodgkin's lymphoma, characterized by multiple lymphomatous polyps along the gastrointestinal tract.
Fernando Ide Yamauchi, MD, Fabíola Moura Moroto Rocha, MD, Eziel Cavalcanti Vasconcelos Rocha, MD, Sheila Aparecida Coelho Siqueira, MD, Manoel de Souza Rocha, MD, PhD   +4 more
doaj   +1 more source