Results 61 to 70 of about 18,113 (219)

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

[Mandibular osteoma in a case of Gardner's syndrome].

, 2011
Gardner's syndrome is characterized by the triad of intestinal polyposis accompanied by multiple hard- and soft-tissue tumors. Untreated, all patients will develop gastrointestinal cancer by the age of 40. Although incurable, progression can be prevented
Fichter, AM;Wolff, KD;Mücke, T
core   +1 more source

Polyposis of gastrointestinal tract after COVID-19 mRNA vaccination: a report of two cases [PDF]

Clinical Endoscopy
Cronkhite-Canada syndrome is a rare gastrointestinal polyposis syndrome with distinctive clinical features and endoscopic findings. Diagnosis can be challenging without suspicion, and the disease carries high mortality due to complications such as ...
Jun Ho Kim, Eun Hye Oh, Dong Soo Han
doaj   +1 more source

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open‐Source Artificial Intelligence Model SEE‐AI

DEN Open, Volume 7, Issue 1, April 2027.
AI‐assisted reading with the open‐source SEE‐AI model improves lesion detection sensitivity and reduces reading time in small‐bowel capsule endoscopy. In a multicenter retrospective study of 249 cases, SEE‐AI provides visual cues that support physicians during interpretation while preserving physician‐led final decisions.
Satoshi Miyazono, Junji Umeno, Tomohiro Nagasue, Takuto Saiki, Hisamitsu Kaku, Takehiro Torisu, Akihito Yokote, Keisuke Kawasaki, Yutaro Ihara, Yuichi Matsuno, Noriyuki Imazu, Tomohiko Moriyama, Ahmed Nashaat Mohamed, Katsuya Hirakawa, Hajime Yamagata, Yasuharu Okamoto, Koichi Kurahara, Shinichiro Yada, Akira Harada, Tetsuro Ago   +19 more
wiley   +1 more source

The Yin and Yang of Invariant Natural Killer T Cells in Tumor Immunity—Suppression of Tumor Immunity in the Intestine

Frontiers in Immunology, 2018
CD1d-restricted invariant natural killer T (iNKT) cells are known as early responding, potent regulatory cells of immune responses. Besides their established role in the regulation of inflammation and autoimmune disease, numerous studies have shown that ...
Ying Wang, Susanna L. Cardell
doaj   +1 more source

Evaluation of Additional Treatment for Residual Cases After Endoscopic Papillectomy of Duodenal Ampullary Tumors

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims This study aimed to assess the prognosis and outcomes of additional treatment for residual adenocarcinoma and adenoma following endoscopic papillectomy (EP) for ampullary tumors. Methods Of 191 patients who underwent EP, 43 with adenocarcinoma or adenoma and either positive or unknown pathological margins were included ...
Yusuke Kurita, Keiki Nagai, Noriki Kasuga, Kensuke Kubota, Yuji Fujita, Yusuke Sekino, Hiroki Uechi, Yuji Koyama, Shintaro Tsujikawa, Shota Matsumoto, Shigeki Tamura, Yu Honda, Shin Yagi, Takeshi Iizuka, Sho Hasegawa, Takamitsu Sato, Kunihiro Hosono, Noritoshi Kobayashi, Yuki Honma, Ryusei Matsuyama, Jotaro Harada, Masato Yoneda, Satoshi Fujii, Itaru Endo, Atsushi Nakajima   +24 more
wiley   +1 more source

K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder [PDF]

, 2011
The human fibroblast growth factor receptor 3 (FGFR3) gene is frequently mutated in superficial urothelial cell carcinoma (UCC). To test the functional significance of FGFR3 activating mutations as a ‘driver’ of UCC, we targeted the expression of mutated
Taketo, M.M., Leung, H.Y., Hing Y. Leung, Wu, X.-R., Iwata, T., Mona Foth, Morris, C.-A., Owen J. Sansom, Lukram Babloo Singh, Tomoko Iwata, Imran Ahmad, Carol-Ann Morris, Makoto Mark Taketo, Singh, L.B., Foth, M., Sansom, O.J., Xue-Ru Wu, Ahmad, I.   +17 more
core   +1 more source

Can innovation in endoscopic therapy alter clinical outcomes in patients with familial adenomatous polyposis?

Endoscopy International Open, 2021
Monique E. van Leerdam, Andrew Latchford
doaj   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

MUTYH Cancer‐Associated Variants Within the Interdomain Connector Differentially Impact Glycosylase Activity and Cellular DNA Repair

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Functional analysis of cancer‐associated variants of the DNA repair enzyme MUTYH in the interdomain connector between the 8‐oxoguanine (OG) recognition and base excision domains reveals discordance between in vitro assays and OG:A repair in cells. This disconnect highlights the use of complementary biochemical and cellular assays to accurately classify
Cindy Khuu, Melody Malek, Savannah G. Conlon, Geoffrey P. Wadey, Carlos H. Trasviña‐Arenas, Sheila S. David   +5 more
wiley   +1 more source