Results 11 to 20 of about 18,113 (219)

Paradoxically Augmented Anti-Tumorigenic Action of Proton Pump Inhibitor and Gastrin in APCMin/+ Intestinal Polyposis Model1

Neoplasia: An International Journal for Oncology Research, 2014
Though long-term administration of proton pump inhibitor (PPI) imposed the risk of gastrointestinal track tumorigenesis by accompanied hypergastrinemia, no overt increases of colon cancer risk were witnessed after a long-term cohort study.
Young-Min Han, Ki Baik Hahm, Jong-Min Park, Sung Pyo Hong, Eun-Hee Kim   +4 more
doaj   +2 more sources

CLINICAL, EPIDEMIOLOGIC, AND ENDOSCOPIC PROFILE IN CHILDREN AND ADOLESCENTS WITH COLONIC POLYPS IN TWO REFERENCE CENTERS [PDF]

Arquivos de Gastroenterologia, 2015
Background - The main goal of this paper is to investigate the frequency, clinical profile, and endoscopic findings of children and teenagers submitted to colonoscopies.
Denise O ANDRADE, Alexandre Rodrigues FERREIRA, Paulo Fernando S BITTENCOURT, Daniela F P RIBEIRO, Rodrigo Gomes da SILVA, Luiz Ronaldo ALBERTI   +5 more
doaj   +2 more sources

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. [PDF]

PLoS Genetics, 2010
Contributions of null and hypomorphic alleles of Apc in mice produce both developmental and pathophysiological phenotypes. To ascribe the resulting genotype-to-phenotype relationship unambiguously to the Wnt/beta-catenin pathway, we challenged the allele
Michael Buchert, Dimitris Athineos, Helen E Abud, Zoe D Burke, Maree C Faux, Michael S Samuel, Andrew G Jarnicki, Catherine E Winbanks, Ian P Newton, Valerie S Meniel, Hiromu Suzuki, Steven A Stacker, Inke S Näthke, David Tosh, Joerg Huelsken, Alan R Clarke, Joan K Heath, Owen J Sansom, Matthias Ernst   +18 more
doaj   +2 more sources

The classification of intestinal polyposis [PDF]

Nature Genetics, 2012
10.1038/ng.2474Nature Genetics4512 ...
Peh Yean, Cheah, Kiat Hon, Lim, Poh Koon, Koh, Choong Leong, Tang   +3 more
openaire   +3 more sources

IL-33 activates tumor stroma to promote intestinal polyposis. [PDF]

Proc Natl Acad Sci U S A, 2015
Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by nonepithelial stromal cells.
Maywald RL, Doerner SK, Pastorelli L, De Salvo C, Benton SM, Dawson EP, Lanza DG, Berger NA, Markowitz SD, Lenz HJ, Nadeau JH, Pizarro TT, Heaney JD.   +12 more
europepmc   +3 more sources

Reply to "The classification of intestinal polyposis"

Nature Genetics, 2012
Tomlinson, I, Jaeger, E, Leedham, S, Thomas, H   +3 more
openaire   +4 more sources

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Dysbiosis-Associated Polyposis of the Colon—Cap Polyposis

Frontiers in Immunology, 2018
Cap polyposis is a rare gastrointestinal disease characterized by multiple inflammatory polyps located between the distal colon and the rectum. Despite the lack of clarity regarding its pathogenesis, mucosal prolapse, chronic inflammatory responses, and ...
Kazuki Okamoto, Tomohiro Watanabe, Yoriaki Komeda, Ayana Okamoto, Kosuke Minaga, Ken Kamata, Kentaro Yamao, Mamoru Takenaka, Satoru Hagiwara, Toshiharu Sakurai, Tomonori Tanaka, Hiroki Sakamoto, Kiyoshige Fujimoto, Naoshi Nishida, Masatoshi Kudo   +14 more
doaj   +1 more source

Polyposis deserves a perfect physical examination for final diagnosis: Bannayan-Riley-Ruvalcaba syndrome

The Turkish Journal of Pediatrics, 2017
Bannayan-Riley-Ruvalcaba syndrome (BRRS) is a rare autosomal dominant inherited polyposis syndrome characterized by macrocephaly, lipomatosis, hemangiomatosis, intestinal polyposis and pigmented macules on penis.
Hayriye Hızarcıoğlu-Gülşen, Esra Kılıç, Elena Dominguez-Garrido, Yusuf Aydemir, Gülen Eda Utine, İnci Nur Saltık-Temizel   +5 more
doaj   +1 more source

Comment on Balsamo et al.: Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature

BMC Medical Genomics, 2022
The publication by Balsamo and colleagues describes a patient with Birt-Hogg-Dubé syndrome and hyperplastic polyposis throughout the gastro-intestinal tract. We question whether the diagnosis of BHD in this patient was justified.
Irma van de Beek, Maurice A. M. van Steensel, Arjan C. Houweling   +2 more
doaj   +1 more source