Results 11 to 20 of about 18,329 (193)

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Dysbiosis-Associated Polyposis of the Colon—Cap Polyposis

Frontiers in Immunology, 2018
Cap polyposis is a rare gastrointestinal disease characterized by multiple inflammatory polyps located between the distal colon and the rectum. Despite the lack of clarity regarding its pathogenesis, mucosal prolapse, chronic inflammatory responses, and ...
Kazuki Okamoto, Tomohiro Watanabe, Yoriaki Komeda, Ayana Okamoto, Kosuke Minaga, Ken Kamata, Kentaro Yamao, Mamoru Takenaka, Satoru Hagiwara, Toshiharu Sakurai, Tomonori Tanaka, Hiroki Sakamoto, Kiyoshige Fujimoto, Naoshi Nishida, Masatoshi Kudo   +14 more
doaj   +1 more source

Polyposis deserves a perfect physical examination for final diagnosis: Bannayan-Riley-Ruvalcaba syndrome

The Turkish Journal of Pediatrics, 2017
Bannayan-Riley-Ruvalcaba syndrome (BRRS) is a rare autosomal dominant inherited polyposis syndrome characterized by macrocephaly, lipomatosis, hemangiomatosis, intestinal polyposis and pigmented macules on penis.
Hayriye Hızarcıoğlu-Gülşen, Esra Kılıç, Elena Dominguez-Garrido, Yusuf Aydemir, Gülen Eda Utine, İnci Nur Saltık-Temizel   +5 more
doaj   +1 more source

Comment on Balsamo et al.: Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature

BMC Medical Genomics, 2022
The publication by Balsamo and colleagues describes a patient with Birt-Hogg-Dubé syndrome and hyperplastic polyposis throughout the gastro-intestinal tract. We question whether the diagnosis of BHD in this patient was justified.
Irma van de Beek, Maurice A. M. van Steensel, Arjan C. Houweling   +2 more
doaj   +1 more source

Gardner syndrome with giant abdominal desmoid tumor during pregnancy: a case report

BMC Surgery, 2020
Background Gardner syndrome is a subtype of familial adenomatous polyposis (FAP), characterized by a combination of adenomatous intestinal polyps and extracolonic lesions such as multiple osteomas, dental abnormalities, and soft tissue tumors.
Liquan Jin, Yunbo Tan, Ziting Su, Shan Huang, Sita Pokhrel, Hongbo Shi, Yiming Chen   +6 more
doaj   +1 more source

CLINICAL, EPIDEMIOLOGIC, AND ENDOSCOPIC PROFILE IN CHILDREN AND ADOLESCENTS WITH COLONIC POLYPS IN TWO REFERENCE CENTERS

Arquivos de Gastroenterologia, 2015
Background - The main goal of this paper is to investigate the frequency, clinical profile, and endoscopic findings of children and teenagers submitted to colonoscopies.
Denise O ANDRADE, Alexandre Rodrigues FERREIRA, Paulo Fernando S BITTENCOURT, Daniela F P RIBEIRO, Rodrigo Gomes da SILVA, Luiz Ronaldo ALBERTI   +5 more
doaj   +1 more source

Modeling APC mutagenesis and familial adenomatous polyposis using human iPS cells. [PDF]

PLoS ONE, 2018
Mutations in the gene Adenomatous Polyposis Coli or APC appear in most sporadic cases of colorectal cancer and it is the most frequent mutation causing hereditary Familial Adenomatous Polyposis.
Cesar A Sommer, Amalia Capilla, Francisco J Molina-Estevez, Andreia Gianotti-Sommer, Nicholas Skvir, Ignacio Caballero, Sanjib Chowdhury, Gustavo Mostoslavsky   +7 more
doaj   +1 more source

The Somatic Mutation Hit on Top of Genetic APC mutations Cause Skin Tumor

Translational Oncology, 2020
Inactivation of the adenomatous polyposis coli (APC) gene is the initiating event in familial adenomatous polyposis (FAP) patients. Up to 90% of FAP patients show intestinal tumors and other extracolonic malignancies including hepatoblastomas, desmoid ...
Ting Niu, Mingming Yang, Qing Liu, Haobin Li, Lingbi Jiang, Fanggu Li, Xiaodong He, Lijing Wang, Jiangchao Li   +8 more
doaj   +1 more source

Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis. [PDF]

PLoS ONE, 2014
Mutations in the WNT-pathway regulator ADENOMATOUS POLYPOSIS COLI (APC) promote aberrant activation of the WNT pathway that is responsible for APC-associated diseases such as Familial Adenomatous Polyposis (FAP) and 85% of spontaneous colorectal cancers (
Bin Li, Colin A Flaveny, Camilla Giambelli, Dennis Liang Fei, Lu Han, Brian I Hang, Feng Bai, Xin-Hai Pei, Vania Nose, Oname Burlingame, Anthony J Capobianco, Darren Orton, Ethan Lee, David J Robbins   +13 more
doaj   +1 more source

Peutz-Jeghers Syndrome without Polyposis

Canadian Journal of Gastroenterology, 1988
Peutz-Jeghers syndrome is generally considered a condition in which familial gastrointestinal polyposis is associated with a characteristic pigmentation of the skin and mucous membranes Two members of a family in which the characteristic pigmentation was
Anthony G. Catto-Smith, Mark K. Patrick, D. Grant Gall   +2 more
doaj   +1 more source