Archives of Pathology & Laboratory Medicine, 2002 Abstract Context.—As rejection in renal transplantation has become better controlled, gastrointestinal complications have become increasingly important. Ischemic colitis and colonic perforation are the most common of these lesions, contributing to morbidity and mortality in the early postoperative period.
Simpson L, Dee +2 more
openaire +2 more sources
N6-Methyladenosine Regulators Promote Malignant Progression of Gastric Adenocarcinoma
Frontiers in Oncology, 2022 N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by methyltransferases, binding proteins, and demethylases. The restoration of m6A to adenosine could result in demethylation modifications.
Yibin Zhao +4 more
doaj +1 more source
Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets [PDF]
, 2017 Background: In this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing.
Casteleyn, Christophe +9 more
core +1 more source
The Paneth Cell: The Curator and Defender of the Immature Small Intestine
Frontiers in Immunology, 2020 Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their cytoplasm.
Shiloh R Lueschow, Steven J. Mcelroy
semanticscholar +1 more source
Diagnostic Pathology, 2021 Background Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers.
Quanlin Liu +6 more
doaj +1 more source
Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]
, 2018 Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S. +5 more
core +1 more source
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model
eLife, 2020 Induction of intestinal drug metabolizing enzymes can complicate the development of new drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in pharmacokinetics, safety and efficacy.
Magdalena Kasendra +13 more
semanticscholar +1 more source
Residual cancer is a strong predictor of survival in T3 incidental gallbladder cancer
BMC Surgery, 2022 Background and purpose Index cholecystectomy is insufficient for curing T3 incidental gallbladder cancer (IGC), and once residual cancer (RC) is found, the prognosis is often poor.
Chuan You +5 more
doaj +1 more source
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis [PDF]
, 2016 During late gestation, villi extend into the intestinal lumen to dramatically increase the surface area of the intestinal epithelium, preparing the gut for the neonatal diet.
Bonder, Edward M. +13 more
core +1 more source
Increased intestinal carbonate precipitate abundance in the sea bream (Sparus aurata L.) in response to ocean acidification [PDF]
, 2019 Marine fish contribute to the carbon cycle by producing mineralized intestinal precipitates generated as by-products of their osmoregulation. Here we aimed at characterizing the control of epithelial bicarbonate secretion and intestinal precipitate ...
Carvalho, Edison S. M. +3 more
core +1 more source