Results 1 to 10 of about 2,312,449 (162)

RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection [PDF]

Journal of Innate Immunity, 2020
Intra-amniotic infection, the invasion of microbes into the amniotic cavity resulting in inflammation, is a clinical condition that can lead to adverse pregnancy outcomes for the mother and fetus as well as severe long-term neonatal morbidities.
Nardhy Gomez-Lopez, Roberto Romero, Aneesha Varrey, Yaozhu Leng, Derek Miller, Bogdan Done, Yi Xu, Gaurav Bhatti, Kenichiro Motomura, Meyer Gershater, Roger Pique-Regi, Adi L. Tarca   +11 more
doaj   +4 more sources

Treatment strategies for intra-amniotic infection and/or inflammation in preterm labor cases [PDF]

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Spontaneous preterm birth (sPTB) is caused by multiple factors; however, the main cause is intra-amniotic infection and/or inflammation. The frequency of intra-amniotic infection/inflammation is higher in extremely sPTB (
Satoshi Yoneda, Noriko Yoneda, Hideki Niimi, Shigeru Saito   +3 more
doaj   +3 more sources

Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review [PDF]

BMC Infectious Diseases, 2022
Background Intra-amniotic infection has a strong causal association with spontaneous preterm birth and preterm prelabor rupture of membranes (PPROM). The most common route of intra-amniotic infection is the ascending pathway in which microorganisms from ...
Piya Chaemsaithong, Waranyu Lertrut, Threebhorn Kamlungkuea, Pitak Santanirand, Arunee Singsaneh, Adithep Jaovisidha, Sasikarn Pakdeeto, Paninee Mongkolsuk, Pisut Pongchaikul   +8 more
doaj   +3 more sources

Intra-Amniotic Infection with Ureaplasma parvum Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin [PDF]

mBio, 2020
Intra-amniotic infection is strongly associated with adverse pregnancy and neonatal outcomes. Most intra-amniotic infections are due to Ureaplasma species; however, the pathogenic potency of these genital mycoplasmas to induce preterm birth is still ...
Kenichiro Motomura, Roberto Romero, Yi Xu, Kevin R. Theis, Jose Galaz, Andrew D. Winters, Rebecca Slutsky, Valeria Garcia-Flores, Chengrui Zou, Dustyn Levenson, Robert Para, Madison M. Ahmad, Derek Miller, Chaur-Dong Hsu, Nardhy Gomez-Lopez   +14 more
doaj   +3 more sources

The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation [PDF]

Frontiers in Cellular and Infection Microbiology
ObjectiveThe objective of this study is to explore whether metagenomic next-generation sequencing (mNGS) and Epithelial Neutrophil Activating Peptide-78 (ENA-78) assays in the amniotic fluid (AF) of patients with preterm labor (PTL) could be employed for
Di Shen, Di Shen, Hui Ju, Hongying Wang, Xietong Wang, Xietong Wang, Guangzhen Li   +6 more
doaj   +4 more sources

Antibiotic administration reduced intra-amniotic inflammation 7 days after preterm premature rupture of the membranes with intra-amniotic infection

The Journal of Maternal-Fetal & Neonatal Medicine, 2023
Objective Intra-amniotic infections increase the risk of preterm delivery and short- and long-term fetal morbidity; however, no consensus exists on the choice of antimicrobial agents as treatment for these infections.
Masazumi Ikeda, Yuko Oshima, Keisuke Tsumura, Kanako Gondo, Takeshi Ono, Yutaka Kozuma, Yukiko Nakura, Itaru Yanagihara, Makoto Nomiyama, Masatoshi Yokoyama   +9 more
doaj   +4 more sources

Rapid diagnosis of intra-amniotic infection using nanopore-based sequencing [PDF]

Journal of Perinatal Medicine, 2023
Objectives: Early diagnosis and treatment of intra-amniotic infection is crucial. Rapid pathogen identification allows for a definite diagnosis and enables proper management.
Arunee Singhsnaeh, Khontawan Pongsuktavorn, Paninee Mongkolsuk   +2 more
exaly   +3 more sources

Late-onset granular intra-amniotic infection following amniotic membrane transplantation [PDF]

American Journal of Ophthalmology Case Reports, 2021
Background: The amniotic membrane (AM) is used in ocular surface reconstruction and is effective at promoting epithelialization and preventing corneal perforation in cases of acute microbial keratitis.
Shaker O. Alreshidi, Samar A. Al-Swailem
doaj   +2 more sources

Plasma inflammatory and immune proteins as predictors of intra-amniotic infection and spontaneous preterm delivery in women with preterm labor: a retrospective study [PDF]

BMC Pregnancy and Childbirth, 2018
Background We investigated whether various inflammatory and immune proteins in plasma predict intra-amniotic infection and imminent preterm delivery in women with preterm labor and compared their predictive ability with that of amniotic fluid (AF ...
Hyunsoo Park, Kyo Hoon Park, Yu Mi Kim, Song Yi Kook, Se Jeong Jeon, Ha-Na Yoo   +5 more
doaj   +2 more sources

Vaginal Infection in Pregnancy Is Associated with Amniotic Oxidative Stress: Insights from AOPP and MDA on Neonatal Outcomes [PDF]

Antioxidants
Amniotic oxidative stress in women with vaginal infection but no documented intra-amniotic infection has received little attention. In this prospective cohort study of 90 women undergoing elective cesarean delivery, 45 had symptomatic, culture- or Nugent-
Meryem Kececi Oguzhanoglu, Icten Olgu Bafali, Kursat Oguzhanoglu, Senem Karacabey Cakmak, Busra Seker Atas, Muhammed Oguz Yildiz, Ali Cetin   +6 more
doaj   +2 more sources