Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes. [PDF]
ObjectiveThe main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) and the presence of ...
Ivana Musilova +7 more
doaj +3 more sources
A Broad Spectrum Chemokine Inhibitor Prevents Preterm Labor but Not Microbial Invasion of the Amniotic Cavity or Neonatal Morbidity in a Non-human Primate Model [PDF]
Leukocyte activation within the chorioamniotic membranes is strongly associated with inflammation and preterm labor (PTL). We hypothesized that prophylaxis with a broad-spectrum chemokine inhibitor (BSCI) would downregulate the inflammatory ...
Michelle Coleman +18 more
doaj +2 more sources
The neutrophil-to-lymphocyte ratio: a marker for microbial invasion of the amniotic cavity in preterm prelabor rupture of membranes [PDF]
Objective This study investigated the relationship between maternal blood neutrophil-to-lymphocyte ratio (NLR), serum C-reactive protein (CRP) levels, and microbial invasion of the amniotic cavity (MIAC) in the context of preterm prelabor rupture of ...
Da Eun Jeong +6 more
doaj +2 more sources
Amniotic and cervical fluids progranulin levels in pregnancies complicated by spontaneous preterm delivery with respect to intra-amniotic complications—a retrospective cohort study [PDF]
The main aim of the study was to determine progranulin levels in amniotic and cervical fluid samples from pregnancies complicated by preterm prelabor rupture of membranes (PPROM) or preterm labor with intact membranes (PTL), with concomitant microbial ...
Ondrej Soucek +7 more
doaj +2 more sources
The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation [PDF]
ObjectiveThe objective of this study is to explore whether metagenomic next-generation sequencing (mNGS) and Epithelial Neutrophil Activating Peptide-78 (ENA-78) assays in the amniotic fluid (AF) of patients with preterm labor (PTL) could be employed for
Di Shen +6 more
doaj +2 more sources
Infections as a Cause of Preterm Birth: Amniotic Fluid Sludge—An Ultrasound Marker for Intra-Amniotic Infections and a Risk Factor for Preterm Birth [PDF]
Preterm labour (PTL) affects about 11% of all deliveries world-wide. It is a major cause of perinatal morbidity and mortality. Although the precise cause is unknown in about 50% of cases, infections are thought to be a major contributing factor.
Mariam Al Baloushi +2 more
doaj +2 more sources
Cord blood procalcitonin and soluble urokinase-type plasminogen activator receptor in predicting histological chorioamnionitis – A pilot study [PDF]
Aims: Chorioamnionitis, caused by microbial invasion of amniotic cavity or sterile inflammation, can lead to prematurity and cytokine storm of fetus known as fetal inflammatory response syndrome (FIRS).
Kati Jalkanen +7 more
doaj +2 more sources
To determine the main clinical characteristics of preterm prelabor rupture of membranes (PPROM) complicated by colonization of the amniotic cavity (microbial invasion of the amniotic cavity without intra-amniotic inflammation).
Marian Kacerovsky +11 more
doaj +1 more source
Objectives: To determine the prevalence and load of Ureaplasma spp. DNA in the cervical fluid of women with singleton pregnancies complicated by preterm prelabor rupture of membranes (PPROM) with respect to intra-amniotic infection, sterile intra ...
Marian Kacerovsky +11 more
doaj +1 more source
A case is reported of Candida glabrata microbial invasion of the amniotic cavity and maternal candidemia with a negative 1,3-β-D-glucan test. A 28-year-old singleton pregnant woman (gravida 1, para 0) presented at 18 weeks and 3 days of gestation ...
Michihisa Shiro +3 more
doaj +1 more source

