Results 1 to 10 of about 8,006 (108)

c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation [PDF]

Frontiers in Cell and Developmental Biology, 2023
Background: Intra-amniotic inflammation (IAI) is associated with increased risk of preterm birth and bronchopulmonary dysplasia (BPD), but the mechanisms by which IAI leads to preterm birth and BPD are poorly understood, and there are no effective ...
April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Claudia O. Rodrigues, Claudia O. Rodrigues, Augusto F. Schmidt   +18 more
doaj   +4 more sources

Quantitative cervicovaginal fluid fetal fibronectin: A liquid biopsy for intra‐amniotic inflammation [PDF]

Acta Obstetricia et Gynecologica Scandinavica
Introduction Intra‐amniotic inflammation is causally linked to spontaneous preterm labor. The gold standard for the diagnosis of intra‐amniotic inflammation is the determination of an amniotic fluid profile obtained from transabdominal amniocentesis ...
Puntabut Warintaksa, Roberto Romero, Waranyu Lertrat, Nutnaree Yuenyongdechawat, Paninee Mongkolsuk, Supakorn Chaiyakarn, Rapeewan Settacomkul, Pisut Pongchaikul, Pornpun Vivithanaporn, Piya Chaemsaithong   +9 more
doaj   +3 more sources

Intra-amniotic inflammation and birth weight in pregnancies with preterm labor with intact membranes: A retrospective cohort study [PDF]

Frontiers in Pediatrics, 2022
ObjectiveTo assess the association between newborn birth weight and the presence of intra-amniotic infection, presence of sterile intra-amniotic inflammation, and absence of intra-amniotic inflammation in pregnancies with preterm labor with intact ...
Jana Matulova, Marian Kacerovsky, Marian Kacerovsky, Radka Bolehovska, Rudolf Kukla, Pavel Bostik, Klara Kolarova, Simona Frydrychová, Bo Jacobsson, Bo Jacobsson, Bo Jacobsson, Ivana Musilova   +11 more
doaj   +2 more sources

Development of a Rat Model of Intra-Amniotic Inflammation via Ultrasound-Guided Administration of a Triggering Agent in the Gestational Sac to Enable Analysis of Individual Amniotic Fluid Samples [PDF]

Frontiers in Pharmacology, 2022
Objectives: To develop a rat model of intra-amniotic inflammation, characterized by the concentration of interleukin-6 in the amniotic fluid, induced by an ultrasound-guided transabdominal administration of lipopolysaccharide into individual gestational ...
Jaroslav Stranik, Marian Kacerovsky, Marian Kacerovsky, Martin Sterba, Ctirad Andrys, Cilia Abad, Frantisek Staud, Stanislav Micuda, Ondrej Soucek, Bo Jacobsson, Bo Jacobsson, Bo Jacobsson, Ivana Musilova   +12 more
doaj   +2 more sources

Intra-Amniotic Inflammation or Infection: Suspected and Confirmed Diagnosis of “Triple I” at Term [PDF]

Children, 2023
Chorioamnionitis (CA) at term of pregnancy can have an infectious and/or inflammatory origin and is associated with adverse outcomes. Triple I (intrauterine inflammation, infection, or both, TI) has been proposed to reduce the overdiagnosis of infection ...
Sara Consonni, Elettra Salmoiraghi, Isadora Vaglio Tessitore, Armando Pintucci, Valentina Vitale, Patrizia Calzi, Francesca Moltrasio, Anna Locatelli   +7 more
doaj   +2 more sources

Effect of a freeze-thaw cycle on amniotic fluid interleukin-6 concentrations in pregnancies with preterm prelabor rupture of membranes: Implications for the diagnosis of intra-amniotic inflammation. [PDF]

PLoS ONE
ObjectivePreterm prelabor rupture of membranes (PPROM) is frequently complicated by intra-amniotic inflammation. Interleukin-6 (IL-6) measured in amniotic fluid is considered the gold-standard biomarker for the diagnosis of this condition; however ...
Richard Spacek, Stepanka Bubenikova, Ivana Musilova, Nikola Kuzniciusova, Karolina Janochova, Michaela Kostelkova, Ladislava Pavlikova, Magdalena Holeckova, Marek Lubusky, Ondrej Simetka, Bo Jacobsson, Marian Kacerovsky   +11 more
doaj   +2 more sources

Immune Cells in the Placental Villi Contribute to Intra-amniotic Inflammation [PDF]

Frontiers in Immunology, 2020
Intra-amniotic (IA) inflammation is associated with significant morbidities for both the mother and the fetus. Prior studies have illustrated many of the effects of IA inflammation on the uterine lining (decidua) and membranous layers of the placenta at ...
Jessica M. Toothaker, Pietro Presicce, Monica Cappelletti, Stephanie F. Stras, Stephanie F. Stras, Collin C. McCourt, Collin C. McCourt, Claire A. Chougnet, Suhas G. Kallapur, Liza Konnikova, Liza Konnikova, Liza Konnikova, Liza Konnikova   +12 more
doaj   +2 more sources

Intra-amniotic inflammation and child neurodevelopment: a systematic review protocol [PDF]

Systematic Reviews, 2018
Background Intra-amniotic inflammation is associated with adverse pregnancy and neonatal outcomes. However, the impact on child neurodevelopment remains unclear. We aim to assess the effect of intra-amniotic inflammation on neurodevelopmental outcomes in
Laurence Soucy-Giguère, Cédric Gasse, Yves Giguère, Suzanne Demers, Emmanuel Bujold, Amélie Boutin   +5 more
doaj   +2 more sources

Quantification of intra-amniotic inflammation in late preterm prelabour rupture of membranes [PDF]

Scientific Reports
Preterm prelabour rupture of membranes (PPROM) complicated by intra-amniotic inflammation (IAI) represents a substantial proportion of preterm birth cases.
Marie Vajrychova, Jaroslav Stranik, Rudolf Kupcik, Michaela Sadibolova, Rudolf Kukla, Radka Bolehovska, Marian Kacerovsky   +6 more
doaj   +2 more sources

Estimated time to emergence of secondary intra-amniotic infection or inflammation since the onset of the preterm premature rupture of membranes

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: Prematurity is the most important prognostic factor for infants born following preterm premature rupture of membranes (PPROM). Therefore, when PPROM occurs between 22 and 33 weeks of gestation, prolonging pregnancy is recommended ...
Satoko Tsuda, Takaaki Shinagawa, Keisuke Tsumura, Kunio So, Fumio Yamasaki, Atsushi Kawaguchi, Yukiko Nakura, Itaru Yanagihara, Makoto Nomiyama, Masatoshi Yokoyama   +9 more
doaj   +1 more source