Results 11 to 20 of about 1,373,251 (190)

Treatment strategies for intra-amniotic infection and/or inflammation in preterm labor cases

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Spontaneous preterm birth (sPTB) is caused by multiple factors; however, the main cause is intra-amniotic infection and/or inflammation. The frequency of intra-amniotic infection/inflammation is higher in extremely sPTB (
Satoshi Yoneda, Noriko Yoneda, Hideki Niimi, Shigeru Saito   +3 more
doaj   +4 more sources

Effects of intra-amniotic lipopolysaccharide and maternal betamethasone on brain inflammation in fetal sheep. [PDF]

PLoS ONE, 2013
RationaleChorioamnionitis and antenatal glucocorticoids are common exposures for preterm infants and can affect the fetal brain, contributing to cognitive and motor deficits in preterm infants. The effects of antenatal glucocorticoids on the brain in the
Elke Kuypers, Reint K Jellema, Daan R M G Ophelders, Jeroen Dudink, Maria Nikiforou, Tim G A M Wolfs, Ilias Nitsos, J Jane Pillow, Graeme R Polglase, Matthew W Kemp, Masatoshi Saito, John P Newnham, Alan H Jobe, Suhas G Kallapur, Boris W Kramer   +14 more
doaj   +9 more sources

Antibiotic administration reduced intra-amniotic inflammation 7 days after preterm premature rupture of the membranes with intra-amniotic infection

The Journal of Maternal-Fetal & Neonatal Medicine, 2023
Objective Intra-amniotic infections increase the risk of preterm delivery and short- and long-term fetal morbidity; however, no consensus exists on the choice of antimicrobial agents as treatment for these infections.
Masazumi Ikeda, Yuko Oshima, Keisuke Tsumura, Kanako Gondo, Takeshi Ono, Yutaka Kozuma, Yukiko Nakura, Itaru Yanagihara, Makoto Nomiyama, Masatoshi Yokoyama   +9 more
doaj   +4 more sources

Preterm labor is characterized by a high abundance of amniotic fluid prostaglandins in patients with intra-amniotic infection or sterile intra-amniotic inflammation. [PDF]

J Matern Fetal Neonatal Med, 2021
To distinguish between prostaglandin and prostamide concentrations in the amniotic fluid of women who had an episode of preterm labor with intact membranes through the utilisation of liquid chromatography-tandem mass spectrometry.
Peiris HN, Romero R, Vaswani K, Reed S, Gomez-Lopez N, Tarca AL, Gudicha DW, Erez O, Maymon E, Mitchell MD.   +9 more
europepmc   +8 more sources

Nicotinamide phosphoribosyltransferase and intra-amniotic inflammation in preterm prelabor rupture of fetal membranes

The Journal of Maternal-Fetal & Neonatal Medicine, 2021
The amniotic fluid nicotinamide phosphoribosyltransferase (NAMPT) levels have not been compared among women with preterm prelabor rupture of membranes (PPROM) comorbid with intra-amniotic infection, sterile intra-amniotic inflammation (IAI), colonization,
Chmelarova, Marcela, Kacerovsky, Marian, Kolackova, Martina, Stranik, Jaroslav, Baranová, Ivana, Andrys, Ctirad, Musilova, Ivana, Jacobsson, Bo,, Drahosova, Marcela   +8 more
core   +3 more sources

Inflammation in fetal sheep from intra-amniotic injection of Ureaplasma parvum

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2010
Collins JJ, Kallapur SG, Knox CL, Nitsos I, Polglase GR, Pillow JJ, Kuypers E, Newnham JP, Jobe AH, Kramer BW. Inflammation in fetal sheep from intra-amniotic injection of Ureaplasma parvum. Am J Physiol Lung Cell Mol Physiol 299: L852-L860, 2010.
Kallapur, Suhas G., Kuypers, Elke, Newnham, John, Polglase, Graeme R., Collins, Jennifer, Elke Kuypers, Knox, Christine, Pillow, Jane, Kramer, Boris, Ilias Nitsos, Newnham, John P., Christine L. Knox, Boris W. Kramer, J. Jane Pillow, Nitsos, Ilias, John P. Newnham, Pillow, J. Jane, Collins, Jennifer J. P., Alan H. Jobe, Jobe, Alan H., Graeme R. Polglase, Jobe, Alan, Polglase, Graeme, Jennifer J. P. Collins, Kallapur, Suhas, Kramer, Boris W., Suhas G. Kallapur, Knox, Christine L.   +27 more
core   +5 more sources

The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation [PDF]

Frontiers in Cellular and Infection Microbiology
ObjectiveThe objective of this study is to explore whether metagenomic next-generation sequencing (mNGS) and Epithelial Neutrophil Activating Peptide-78 (ENA-78) assays in the amniotic fluid (AF) of patients with preterm labor (PTL) could be employed for
Di Shen, Di Shen, Hui Ju, Hongying Wang, Xietong Wang, Xietong Wang, Guangzhen Li   +6 more
doaj   +2 more sources

Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2012
Kuypers E, Collins JJ, Kramer BW, Ofman G, Nitsos I, Pillow JJ, Polglase GR, Kemp MW, Newnham JP, Gavilanes AW, Nowacki R, Ikegami M, Jobe AH, Kallapur SG. Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs.
Ikegami, Machiko, Kallapur, Suhas G., Kuypers, Elke, Polglase, Graeme R., Kemp, Matthew W., Elke Kuypers, Antonio W. D. Gavilanes, Gavilanes, Antonio W. D., Matthew W. Kemp, Ilias Nitsos, Newnham, John P., Boris W. Kramer, Relana Nowacki, J. Jane Pillow, Nitsos, Ilias, John P. Newnham, Pillow, J. Jane, Machiko Ikegami, Collins, Jennifer J. P., Alan H. Jobe, Jobe, Alan H., Graeme R. Polglase, Ofman, Gaston, Jennifer J. P. Collins, Kramer, Boris W., Suhas G. Kallapur, Gaston Ofman, Nowacki, Relana   +27 more
core   +5 more sources

The cytokine prokineticin-1 in preterm labor with and without intra-amniotic inflammation

Journal of Perinatal Medicine
Prokineticin 1 (PROK1), known as endocrine gland-derived endothelial growth factor (EG-VEGF), is a key regulator of pregnancy, playing various roles from implantation to birth.
Desseux Morgane, Raia-Barjat Tiphaine, Romero Roberto, Hoffmann Pascale, Meyyazhagan Arun, Awonuga Awoniyi O., Chaiworapongsa Tinnakorn, Benharouga Mohamed, Alfaidy Nadia   +8 more
doaj   +3 more sources

Intra-amniotic inflammation in the mid-trimester of pregnancy is a risk factor for neuropsychological disorders in childhood. [PDF]

J Perinat Med, 2023
Objectives: Intra-amniotic inflammation is a subclinical condition frequently caused by either microbial invasion of the amniotic cavity or sterile inflammatory stimuli, e.g., alarmins. An accumulating body of evidence supports a role for maternal immune
Gervasi MT, Romero R, Cainelli E, Veronese P, Tran MR, Jung E, Suksai M, Bosco M, Gotsch F.   +8 more
europepmc   +2 more sources