Results 191 to 200 of about 3,033,431 (331)

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

The Parkinson's drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis. [PDF]

NPJ Antimicrob Resist
Sahile HA, Christofferson M, Alford MA, Rens C, Haghdadi H, Chao JD, Langdon G, Hancock REW, Chen J, Av-Gay Y.   +9 more
europepmc   +1 more source

IV. Tonsillar Tubercles Containing Intracellular Concretions Simulating Foreign Body Pseudotubercles [PDF]

, 1922
Carl Vernon Weller
openalex   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Trehalose-loaded LNPs enhance mRNA stability and bridge in vitro in vivo efficacy gap. [PDF]

NPJ Vaccines
Liu XH, Song HP, Tao LL, Zhai Z, Huang JX, Cheng YX.   +5 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Valproic Acid Promotes the Differentiation of Satellite Glial Cells into Neurons via the pH-Dependent Pathway. [PDF]

Biomolecules
Wang D, Kang W, Zhang J, Xu J, Wang R, Xiao X, Wei C, Yu W, Lu J.   +8 more
europepmc   +1 more source

The Intracellular Enzymes of Lower Fungi, Especially those of Penicillium Camemberti

, 1909
Arthur W. Dox
openalex   +1 more source

SPECIFIC INTRACELLULAR BINDING OF RUBIDIUM BY RAT DIAPHRAGM MUSCLE [PDF]

, 1959
P. Menozzi, David Norman, A Polleri, Gillian M. Schiralli Lester, Oscar Hechter   +4 more
openalex   +1 more source

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Biochemical Journal, 1955
B. C. D. Duve, B. C. Pressman, R., Gianetto, R. Wattiaux   +4 more
semanticscholar   +1 more source