Results 41 to 50 of about 3,143,322 (333)

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]

open access: yes, 2016
Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel   +4 more
core   +1 more source

GENETIC PROFILE STAPHYLOCOCCUS AUREUS, ISOLATED FROM BACTERIAL CARRIERS AND PATIENTS WITH INFECTIOUS INFLAMMATORY PATHOLOGY

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. A comparative genetic evaluation of the pathogenic potential of Staphylococcus aureus strains isolated from bacterial carriers and patients with infectious inflammatory pathology. Materials and methods. The presence of pathogenicity genes (ssp, spa,
V. A. Gritsenko   +5 more
doaj   +1 more source

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts.

open access: yesChemical Reviews, 2018
Intracellular delivery is a key step in biological research and has enabled decades of biomedical discoveries. It is also becoming increasingly important in industrial and medical applications ranging from biomanufacture to cell-based therapies. Here, we
Martin P. Stewart, R. Langer, K. Jensen
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

In Vitro Stability of Phytase from Recombinant Bacteria E. Coli BL21 (DE3) EAS1-AMP [PDF]

open access: yes, 2011
The objective of the research was to inquire the Km, Vm, activity, intracellular phytase stability exposed to pH variation, temperature variation and protease (pepsin and pancreas) in vitro.
Bachruddin, Z.   +3 more
core  

Intracellular mechanochemical waves in an active poroelastic model [PDF]

open access: yes, 2013
Many processes in living cells are controlled by biochemical substances regulating active stresses. The cytoplasm is an active material with both viscoelastic and liquid properties. We incorporate the active stress into a two-phase model of the cytoplasm
Alonso Muñoz, Sergio   +3 more
core   +2 more sources

PHYSIOLOGICAL FEATURES OF CORYNEBACTERIA OF FEMALE REPRODUCTIVE TRACT

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Literature data and results of authors’ research on biological properties of corynebacteria of reproductive tract of women are analyzed. General characteristics of microorganisms is given. 20 species of corynebacteria are presented: C.
L. V. Gladysheva, S. V. Cherkasov
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Finite-size effects in intracellular microrheology

open access: yes, 2006
We propose a model to explain finite-size effects in intracellular microrheology observed in experiments. The constrained dynamics of the particles in the intracellular medium, treated as a viscoelastic medium, is described by means of a diffusion ...
Gadomski A.   +3 more
core   +1 more source

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

open access: yes, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

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