Results 1 to 10 of about 689,040 (308)

Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential [PDF]

open access: yesBMC Neuroscience, 2008
Background Factors that regulate intracellular calcium concentration are known to play a critical role in brain function and neural development, including neural plasticity and neurogenesis.
Brinton Roberta, Wang Jun
doaj   +3 more sources

Physiology of intracellular calcium buffering.

open access: yesPhysiol Rev, 2023
Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is bound to buffers, with typically only ∼1% being freely ionized at resting levels in most cells. Physiological Ca2+ buffers include small molecules and proteins, and experimentally Ca2+ indicators will also buffer calcium.
Eisner D   +3 more
europepmc   +5 more sources

Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic

open access: yesPLoS ONE, 2022
Many anesthetics, including Propofol, have been reported to induce elevation of intracellular calcium, and we were interested to investigate the possible contribution of calcium elevation to the mechanism of the newly approved remimazolam actions ...
Tomoaki Urabe   +8 more
doaj   +2 more sources

Intracellular calcium signaling [PDF]

open access: yesJournal of Cell Science, 2002
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
openaire   +2 more sources

Internalization of apoptotic cells during efferocytosis requires Mertk-mediated calcium influx

open access: yesCell Death and Disease, 2023
Phagocytosis of apoptotic cells, called efferocytosis, requires calcium inside and outside of phagocytes. Due to its necessity, calcium flux is sophisticatedly modulated, and the level of intracellular calcium in phagocytes is ultimately elevated during ...
Susumin Yang   +8 more
doaj   +1 more source

Measurement of Intracellular Calcium [PDF]

open access: yesPhysiological Reviews, 1999
To a certain extent, all cellular, physiological, and pathological phenomena that occur in cells are accompanied by ionic changes. The development of techniques allowing the measurement of such ion activities has contributed substantially to our understanding of normal and abnormal cellular function.
A, Takahashi   +3 more
openaire   +2 more sources

Calcineurin-mediated intracellular organelle calcium homeostasis is required for the survival of fungal pathogens upon extracellular calcium stimuli

open access: yesVirulence, 2021
In eukaryotes, calcium not only is an essential mineral nutrient but also serves as an intracellular second messenger that is necessary for many physiological processes. Previous studies showed that the protein phosphatase-calcineurin protects fungi from
Chi Zhang   +5 more
doaj   +1 more source

Circulating IgGs in Type 2 Diabetes with Atrial Fibrillation Induce IP3-Mediated Calcium Elevation in Cardiomyocytes

open access: yesiScience, 2020
Summary: Higher risk of cardiac arrhythmias including atrial fibrillation (AF) associates with type 2 diabetes mellitus (T2DM) with the underlying mechanism largely unknown.
Yanhong Luo   +5 more
doaj   +1 more source

Refilling intracellular calcium stores [PDF]

open access: yesDrug Discovery Today: Disease Mechanisms, 2010
Within the cardiac cell, the movements of calcium ions are tightly regulated by a number of regulatory proteins including pumps, and channels. The sarcoplasmic reticulum (SR) is in large part responsible for orchestrating these movements for the normal functioning of the cardiomyocyte.
Changwon, Kho   +3 more
openaire   +2 more sources

Effect of calcium electroporation in combination with metformin in vivo and correlation between viability and intracellular ATP level after calcium electroporation in vitro. [PDF]

open access: yesPLoS ONE, 2017
BACKGROUND:Calcium electroporation is a new experimental anti-cancer treatment where calcium is internalized into cells by application of short, high voltage pulses.
Stine Krog Frandsen, Julie Gehl
doaj   +1 more source

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