Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Chilling Does Not Affect the Functionality of Intracellular Calcium Stores in Viable Boar Sperm During Liquid Preservation. [PDF]
Int J Mol SciBui DH +3 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Intracellular calcium imaging for agonist screening. [PDF]
Biophys RepWang H, Yang B, Mo L, Yang HQ.
europepmc +1 more source
From Bug to Feature: Harnessing Cross‐Sensitivity for Multiparametric Luminescence Sensing
Advanced Functional Materials, EarlyView.Cross‐sensitivity in luminescence sensing is reframed from a limitation into a resource for multiparametric detection. Using ruby microspheres as a model system, cross‐sensitivity is quantitatively assessed and exploited through linear discriminant analysis, enabling simultaneous, correction‐free pressure and temperature sensing with a single ...
Nikita Panov +5 more
wiley +1 more source
Evaluating the electrical stimulation of bone cells based on an induced transmembrane potential model and intracellular calcium levels. [PDF]
J Tissue EngBielfeldt M +8 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song +11 more
wiley +1 more source
Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality. [PDF]
iScienceSchlautmann L +15 more
europepmc +1 more source
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
Cannabinoid Ligand-Mediated Glycogen Depletion in Astrocytes Is Associated With Increased Intracellular Calcium, Energy Metabolism, and Membrane Dynamics. [PDF]
J NeurochemFink K, Zorec R, Kreft M.
europepmc +1 more source