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Intracellular Calcium Homeostasis and Signaling

2012
Ca(2+) is a universal carrier of biological information: it controls cell life from its origin at fertilization to its end in the process of programmed cell death. Ca(2+) is a conventional diffusible second messenger released inside cells by the interaction of first messengers with plasma membrane receptors. However, it can also penetrate directly into
BRINI, MARISA   +3 more
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Calcium receptor-mediated intracellular signalling

Cell Calcium, 2004
As a G protein-coupled receptor (GPCR), the extracellular calcium-sensing receptor (CaR) responds to changes in extracellular free calcium concentration by inducing intracellular signalling. These CaR-induced signals then specifically modulate cellular functions such as parathyroid hormone secretion from the parathyroid glands and calcium reabsorption ...
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Calmodulin—an intracellular calcium receptor

Nature, 1980
Calmodulin, a protein that binds calcium with high affinity and specificity, is structurally conserved and functionally preserved throughout the animal and plant kingdoms. It serves as an intracellular Ca2+-receptor and mediates the Ca2+ regulation of cyclic nucleotide and glycogen metabolism, secretion, motility and Ca2+ transport.
A R, Means, J R, Dedman
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Intracellular Calcium and Cell Function

Annual Review of Nutrition, 1989
INTRODUCTION 347 MEASUREMENT OF INTRACELLULAR Ca 348 Measurement of Total Cell Ca and Ca Fluxes 348 Ca·Sensitive Optical Probes and Microelectrodes 349 Ca-Sensitive Fluorescent Probes 349 REGULATION OF INTRACELLULAR Ca LEVELS 351 Ca Channels 351 Release from Intracellular Ca Stores 352 Alternative Pathways for Mobilizing Intracellular Ca ...
M L, Villereal, H C, Palfrey
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Vitamin D and Intracellular Calcium

1998
The role of the hormonally active form of vitamin D, 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3], in the regulation of Ca2+ metabolism is well established (Norman, 1979; Spirichev and Sergeev, 1988). Current concepts of the vitamin D- and intracellular Ca2+-mediated signaling are based on steroid and second messenger dogmas.
I N, Sergeev   +2 more
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Calcium | Intracellular Calcium Waves

2021
Jong T. Chun   +2 more
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Methods of Measuring Intracellular Calcium

1979
Publisher Summary This chapter discusses the methods of measuring intracellular calcium. The techniques described offer a wide range of approaches for assaying intracellular Ca 2+ . The variety of problems involved in monitoring in vivo Ca diffusion among compartments in the short period of the physiological event present peculiar technical ...
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Locating intracellular calcium stores

Trends in Biochemical Sciences, 1991
R D, Burgoyne, T R, Cheek
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Intracellular Calcium Signaling

2010
Harzheim, D., Roderick, H., Bootman, M.
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