Results 31 to 40 of about 689,040 (308)

Cadmium induces transcription independently of intracellular calcium mobilization.

PLoS ONE, 2011
BackgroundExposure to cadmium is associated with human pathologies and altered gene expression. The molecular mechanisms by which cadmium affects transcription remain unclear.
Brooke E Tvermoes, Gary S Bird, Jonathan H Freedman   +2 more
doaj   +1 more source

Leptin-Induced Endothelium-Independent Vasoconstriction in Thoracic Aorta and Pulmonary Artery of Spontaneously Hypertensive Rats: Role of Calcium Channels and Stores. [PDF]

PLoS ONE, 2017
Decreased leptin-induced endothelium-dependent vasodilation has been reported in spontaneously hypertensive rats (SHR). Here, we report leptin-induced vasoconstriction in endothelium-denuded pulmonary artery and thoracic aorta from SHR and sought to ...
Samantha Gomart, Caroline Gaudreau-Ménard, Pascale Jespers, Omer Gurkan Dilek, Emeline Hupkens, Aliénor Hanthazi, Robert Naeije, Christian Melot, Nathalie Labranche, Laurence Dewachter, Kathleen Mc Entee   +10 more
doaj   +1 more source

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium [PDF]

, 2013
Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such
A Gnoni, A Pace, A Sharma, AJ Hietaranta, AK Saluja, AK Saluja, AS Gukovskaya, B Han, B Han, B Hofbauer, B Kruger, C Schafer, Catherine J. Baty, CH Kubisch, Chandra Durgampudi, Chathur Acharya, DN Criddle, Donna B. Stolz, EC Thrower, EM Parker, F Gorelick, F Mooren, F Nozu, G Lynch, H Weber, HK Baumgartner, I Gukovsky, I Gukovsky, I Samuel, JA Tapia, JA Williams, Jenny Karlsson, JV Gerasimenko, KA Muili, Krutika Patel, L Fischer, L Orlichenko, Lidiya Orlichenko, LJ Christopher, LJ Lombardo, LS Orlichenko, M Sendler, MS O'Konski, OA Mareninova, OH Petersen, Pawan Noel, PC Redondo, Rachel Cline, Ram Narayan Trivedi, RD Duan, RR Torgerson, RR Torgerson, S Kawabata, S Navina, Sarah Navina, SD Waterford, SG Weller, SJ Pandol, Sohail Z. Husain, Stuart E. Dryer, SZ Husain, SZ Husain, T Eley, T Grady, T Grady, V Sancho, Vijay P. Singh, Vivek Mishra, VP Singh, VP Singh, VP Singh, VP Singh, Y Tsunoda   +72 more
core   +4 more sources

Control of Intracellular Calcium Signaling as a Neuroprotective Strategy

Molecules, 2010
Both acute and chronic degenerative diseases of the nervous system reduce the viability and function of neurons through changes in intracellular calcium signaling.
R. Scott Duncan, Daryl L. Goad, Michael A. Grillo, Simon Kaja, Andrew J. Payne, Peter Koulen   +5 more
doaj   +1 more source

Glucose metabolism and oscillatory behavior of pancreatic islets [PDF]

, 2005
A variety of oscillations are observed in pancreatic islets.We establish a model, incorporating two oscillatory systems of different time scales: One is the well-known bursting model in pancreatic beta-cells and the other is the glucose-insulin feedback ...
A. L. Hodgkin, B. A. Cunningham, B. Hellman, D. S. Koh, H. J. Kim, H. Kang, J. Jo, J. N. Weiss, J. Sturis, J. V. Sánchez-Andrés, L. J. DelFelice, L. W. Maki, L. W. Maki, M. Valdeolmillos, M. Y. Choi, P. Bergsten, P. Gilon, P. Smolen, S. Dryselius, S. W. Rhee   +19 more
core   +1 more source

Calcium spiking patterns and the role of the calcium/calmodulin-dependent kinase CCaMK in lateral root base nodulation of Sesbania rostrata [PDF]

, 2009
Nodulation factor (NF) signal transduction in the legume-rhizobium symbiosis involves calcium oscillations that are instrumental in eliciting nodulation.
Capoen, Ward, Den Herder, Jeroen, Sun, Jongho, Verplancke, Christa, De Keyser, Annick, De Rycke, Riet, Goormachtig, Sofie, Oldroyd, Giles, Holsters, Marcella   +8 more
core   +2 more sources

Translating intracellular calcium signaling into models [PDF]

, 2014
The rich experimental data on intracellular calcium has put theoreticians in an ideal position to derive models of intracellular calcium signaling. Over the last 25 years, a large number of modeling frameworks have been suggested.
Thul, Ruediger
core   +2 more sources

Glucose and glycogen affects Ca2+ transient during fatigue to a greater extent in the least than in the most fatigue resistant mouse FDB fibers

Physiological Reports
The overall objective was to determine how no extracellular glucose and/or low glycogen content affect fatigue kinetics in mouse flexor digitorum brevis (FDB) single muscle fibers.
Erik Hesse, Tarek Ammar, Jean‐Marc Renaud   +2 more
doaj   +1 more source

Numerical analysis of arterial contraction regulated by smooth muscle stretch and intracellular calcium ion concentration

Journal of Biomechanical Science and Engineering, 2014
In this study, for a better understanding of arterial functions, we examine the effects of active stresses, which are generated by contractile units included in smooth muscle cells, on the stress distribution in the arterial wall.
Naoki KIDA, Taiji ADACHI
doaj   +1 more source

TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. [PDF]

PLoS ONE, 2015
Intracellular calcium signaling is critical for initiating and sustaining diverse cellular functions including transcription, synaptic signaling, muscle contraction, apoptosis and fertilization.
Prashant B Shambharkar, Mark Bittinger, Brian Latario, ZhaoHui Xiong, Somnath Bandyopadhyay, Vanessa Davis, Victor Lin, Yi Yang, Reginald Valdez, Mark A Labow   +9 more
doaj   +1 more source