Results 81 to 90 of about 689,040 (308)
The involvement of TRP channels in bone homeostasis
Frontiers in Endocrinology, 2012 Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium ...
Liesbet eLieben, Geert eCarmeliet
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Characterization of Transepithelial Potential Oscillations in the \u3cem\u3eDrosophila\u3c/em\u3e Malpighian Tubule [PDF]
, 2001 The Malpighian tubule of Drosophila melanogaster is a useful model system for studying the regulation of epithelial ion transport. In acutely isolated tubules, the transepithelial potential (TEP) undergoes large oscillations in amplitude with a period of
Blumenthal, Edward M
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Duramycin-induced calcium release in cancer cells [PDF]
, 2015 Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood.
Broughton, Laura J. +3 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
, 2012 Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
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Calcium as an Intracellular Regulator [PDF]
Proceedings of the Nutrition Society, 1988 The survival and reproduction of human life requires calcium, not only outside the cell for maintenance of skeletal and tissue architecture, and for key extracellular enzymes such as those involved in blood clotting or digestion, but also inside cells controlling their behaviour (Campbell 1983).
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The BSA-induced Ca(2+) influx during sperm capacitation is CATSPER channel-dependent
Reproductive Biology and Endocrinology, 2009 Background Serum albumin is a key component in mammalian sperm capacitation, a functional maturation process by which sperm become competent to fertilize oocytes.
Ren Dejian, Xia Jingsheng
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Primary male osteoporosis is associated with enhanced glucocorticoid availability [PDF]
, 2017 Objective. While systemic glucocorticoids compromise bone metabolism, altered intracellular cortisol availability may also contribute to the pathogenesis of primary male osteoporosis (MO).
Arampatzis, Spyridon +3 more
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Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]
, 1992 We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J. +3 more
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