Results 81 to 90 of about 3,145,194 (361)

Changes in membrane lipids drive increased endocytosis following Fas ligation [PDF]

open access: yes, 2017
Once activated, some surface receptors promote membrane movements that open new portals of endocytosis, in part to facilitate the internalization of their activated complexes.
Degli Esposti, Mauro   +9 more
core   +1 more source

Coupled Response of Membrane Hydration with Oscillating Metabolism in Live Cells: An Alternative Way to Modulate Structural Aspects of Biological Membranes?

open access: yesBiomolecules, 2019
We propose that active metabolic processes may regulate structural changes in biological membranes via the physical state of cell water. This proposition is based on recent results obtained from our group in yeast cells displaying glycolytic oscillations,
Luis A. Bagatolli   +2 more
doaj   +1 more source

Targeted Delivery of Amoxicillin to C. trachomatis by the Transferrin Iron Acquisition Pathway. [PDF]

open access: yesPLoS ONE, 2016
Weak intracellular penetration of antibiotics makes some infections difficult to treat. The Trojan horse strategy for targeted drug delivery is among the interesting routes being explored to overcome this therapeutic difficulty. Chlamydia trachomatis, as
Jun Hai   +7 more
doaj   +1 more source

Shuttling of G Protein Subunits between the Plasma Membrane and Intracellular Membranes*

open access: yesJournal of Biological Chemistry, 2007
Heterotrimeric G proteins (αβγ) mediate the majority of signaling pathways in mammalian cells. It is long held that G protein function is localized to the plasma membrane.
M. Chisari   +3 more
semanticscholar   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]

open access: yes, 2010
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core   +1 more source

Inositol 1,4,5-trisphosphate-induced release of sequestered Ca2+ from highly purified human platelet intracellular membranes.

open access: yesBiochemical Journal, 1985
Evidence has accumulated in support of a role for intracellularly generated inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] in raising cytosol [Ca2+] when various hormones, neurotransmitters, growth factors and other stimulants act on cell surfaces.
K. Authi, N. Crawford
semanticscholar   +1 more source

Membrane Stimulation and Intracellular Killing by Monocytes

open access: yesImmunobiology, 1982
The present paper reviews our recent studies concerning the intracellular killing of bacteria by human monocytes and compares the results with those found for circulating granulocytes. The findings show that optimal intracellular killing of catalase-positive and catalase-negative bacteria is only reached during interaction of the Fc part of IgG and ...
Peter C. J. Leijh, R. Van Furth
openaire   +3 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Membrane Preparation, Sucrose Density Gradients and Two-phase Separation Fractionation from Five-day-old Arabidopsis seedlings

open access: yesBio-Protocol, 2013
Membrane preparation has been widely used for characterization the membrane proteins. Membrane fractions can be separated by a combination of differential and density-gradient centrifugation techniques (Hodges et al., 1972; Leonard and Vanderwoude, 1976).
Haibing Yang, Angus Murphy
doaj   +1 more source

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