Intracellular artificial supramolecules based on de novo designed Y15 peptides
Nature Communications, 2021 Self-assembling peptides (SAPs) can be used to build biomaterials, but genetically encoded SAPs have rarely been used as building blocks in cells.
Takayuki Miki +5 more
doaj +2 more sources
Pectin Structural Dynamics: Developmental and Evolutionary Perspectives [PDF]
PlantsPlant cell walls play a crucial role in plant development and evolution. This structure is primarily composed of proteins and polysaccharides, including cellulose, hemicellulose, and pectins. Homogalacturonan (HG), the most abundant pectin in the primary
Zúñiga-Sánchez Esther +2 more
doaj +2 more sources
A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]
, 2010 Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
core +6 more sources
Discovery and quantification of proteins of biological relevance through differential proteomics and biosensing [PDF]
, 2012 Medical diagnosis is the process of attempting to determine and/or identify a possible disease or disorder. This process is revealed by biomarkers, defined by The Food and Drug Administration (FDA) as “characteristics that are objectively measured and
Lonardoni, Francesco
core +7 more sources
Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases [PDF]
Diabetes & Metabolism Journal, 2023 Mitochondria are complex metabolic organelles with manifold pathophysiological implications in diabetes. Currently published mitochondrial-encoded peptides, which are expressed from the mitochondrial open reading frame of the 12S ribosomal RNA type-c ...
Byung Soo Kong +2 more
doaj +1 more source
iScience, 2022 Summary: The mitogen-activated protein kinase (MAPK) intracellular signaling pathway mediates numerous biological processes, including antimicrobial immune response by inducing antimicrobial peptides (AMPs) production.
Jude Juventus Aweya +9 more
doaj +1 more source
Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes [PDF]
Journal of Virology, 2005 ABSTRACT The hepatitis C virus (HCV) p7 protein forms an amantadine-sensitive ion channel required for viral replication in chimpanzees, though its precise role in the life cycle of HCV is unknown. In an attempt to gain some insights into p7 function, we examined the intracellular localization of p7 using epitope tags and an anti-p7 peptide ...
Griffin, Stephen +4 more
openaire +3 more sources
Digoxigenin-Labeled Peptides for the Immunological Quantification of Intracellular Signaling Proteins: Application to the MAP Kinase Kinase Isoform MEK2 [PDF]
BioTechniques, 1997 Two competitive enzyme immunoassays using digoxigenin-labeled peptides have been developed for the quantification of the protein kinase MEK2 in cell extracts. Rabbit polyclonal antibodies directed against either the amino-terminal or proline-rich amino acid sequences of MEK2 were used for the immunoconcentration of the protein.
Charles Blais +4 more
openaire +3 more sources
Food Science and Human Wellness, 2022 Soy consumption has been associated with potential health benefits in reducing chronic diseases. These physiological functions have been attributed to soy proteins or more commonly to bioactive peptides.
Yinghuan Wu +5 more
doaj +1 more source
Analysis of the Yeast Peptidome and Comparison with the Human Peptidome. [PDF]
PLoS ONE, 2016 Peptides function as signaling molecules in species as diverse as humans and yeast. Mass spectrometry-based peptidomics techniques provide a relatively unbiased method to assess the peptidome of biological samples.
Sayani Dasgupta +7 more
doaj +1 more source