Results 261 to 270 of about 1,288,434 (306)

Monitoring intracellular transport

Journal of Theoretical Biology, 1975
Abstract Ingested plastic scintillator spheres are shown to be a useful tool for investigating intracellular transport of material labelled by a weak beta emitter. It is found that-by numerically solving a linear integral equation with known kernel-the time evolution of the intracellular emitter density profile in the vicinity of the cell membrane is
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Intracellular transport and metabolism of sphingomyelin

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991
SM is unique among the phospholipids because it is restricted to the lumenal aspect of organelles involved in the secretory and endocytic pathways. Given the intracellular sites of SM biosynthesis and hydrolysis, and the interconnections between these sites by vesicle-mediated transport pathways, the basic mechanism for maintaining the intracellular ...
M, Koval, R E, Pagano
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Intracellular transport of bile acids

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000
Bile acids originate from the liver and are transported via bile to the intestines where they perform an important role in the absorption of lipids and lipid-soluble nutrients. Most of the bile acids are reclaimed from the terminal ileum and returned to the liver via portal blood for reuse.
L B, Agellon, E C, Torchia
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Intracellular Lipid Transport In Eukaryotes

Annual Review of Physiology, 1987
The metabolic regulation and biological significance of the large number of lipid species found in all biological membranes are not well understood. It has been estimated that there are greater than 1000 chemically distinct phospho­ lipid species in eukaryotic cells (98), all of which must bestow significant evolutionary advantages to the cells.
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Regulation of intracellular membrane transport

Current Opinion in Cell Biology, 1992
A number of proteins that are necessary for membrane transport have been identified using cell-free assays and yeast genetics. Although our knowledge of transport mechanisms remains limited, common themes are clearly emerging. In particular, specific GTP-binding proteins appear to be involved, not only at all steps of membrane traffic but also at more ...
J, Gruenberg, M J, Clague
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Modeling of Intracellular Transport and Compartmentation

2011
The complexity and internal organization of mammalian cells as well as the regulation of intracellular transport processes has increasingly moved into the focus of investigation during the past two decades. Advanced staining and microscopy techniques help to shed light onto spatial cellular compartmentation and regulation, increasing the demand for ...
Uwe, Jandt, An-Ping, Zeng
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Intracellular sterol transport and distribution

Current Opinion in Cell Biology, 2006
Sterols are important components of many biological membranes, and changes in sterol levels can have dramatic effects on membrane properties. Sterols are transported rapidly between cellular organelles by vesicular and nonvesicular processes. Recent studies have identified transmembrane proteins that facilitate the removal of sterols from membranes as ...
Frederick R, Maxfield, Anant K, Menon
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Cytoskeletal elements and intracellular transport

Journal of Cellular Biochemistry, 2007
AbstractRecent advances in the understanding of the functions of various components of the cytoskeleton indicate that, besides serving a structural role, the cytoskeletal elements may regulate the transport of several proteins in the cell. Studies reveal that there are co‐operative interactions between the actin and microtubule cytoskeletons including ...
Lakshmi, Bhaskar, Vidya S, Krishnan, Raghava Varman, Thampan   +2 more
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Membrane tethering in intracellular transport

Current Opinion in Cell Biology, 1999
Studies of various membrane trafficking steps over the past year indicate that membranes are tethered together prior to the interaction of v-SNAREs and t-SNAREs across the membrane junction. The tethering proteins identified to date are quite large, being either fibrous proteins or multimeric protein complexes.
M G, Waters, S R, Pfeffer
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Intracellular Transport of Pancreatic Enzymes

Scandinavian Journal of Gastroenterology, 1996
Most pancreatic secretory proteins are packaged within the trans-Golgi network into zymogen granules, which are secreted in a regulated manner by exocytosis. But others enter alternative, constitutive-like pathways directed towards both apical and basolateral membranes.
L J, Cook, O A, Musa, R M, Case
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