Results 91 to 100 of about 500,548 (294)

Toward Automated Detection of Microbleeds with Anatomical Scale Localization: A Complete Clinical Diagnosis Support Using Deep Learning [PDF]

arXiv, 2023
Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline, intracerebral hemorrhage, and cerebral infarction.
arxiv  

Splenectomy Improves Outcome of Intracerebral Hemorrhage. [PDF]

FASEB J
In this in vivo study, mice were divided into splenectomy and laparotomy groups (control), and ICH was induced 2 weeks after. It is demonstrated that ICH products such as blood trigger an acute splenic response, leading to immune cell infiltration into the peri‐hematomal region, which in turn causes neuroinflammation and damage to blood‐brain barrier ...
Leung CH, Shek HT, Liu J, Kiang KM, Leung GK.   +4 more
europepmc   +2 more sources

An Intracerebral Hemorrhage Care Bundle Is Associated with Lower Case Fatality

Annals of Neurology, 2019
Anticoagulation reversal, intensive blood pressure lowering, neurosurgery, and access to critical care might all be beneficial in acute intracerebral hemorrhage (ICH).
A. Parry-Jones, C. Sammut-Powell, Kyriaki Paroutoglou, Emily Birleson, J. Rowland, S. Lee, L. Cecchini, M. Massyn, R. Emsley, B. Bray, H. Patel   +10 more
semanticscholar   +1 more source

Low-density lipoprotein cholesterol and risk of intracerebral hemorrhage

Neurology, 2019
Objective To prospectively examine the association between low-density lipoprotein (LDL) cholesterol (LDL-C) concentrations and intracerebral hemorrhage (ICH) risk.
Chaoran Ma, M. Gurol, Zhe Huang, A. Lichtenstein, Xiuyan Wang, Yuzhen Wang, Samantha Neumann, Shouling Wu, Xiang Gao   +8 more
semanticscholar   +1 more source

Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage

European Journal of Neurology, Volume 30, Issue 1, Page 116-124, January 2023., 2023
Abstract Background and purpose Nuclear factor erythroid 2‐related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance.
Ben Gaastra, Poppy Duncan, Mark K. Bakker, Isabel C. Hostettler, Varinder S. Alg, Henry Houlden, Ynte M. Ruigrok, Ian Galea, Will Tapper, David Werring, Diederik Bulters   +10 more
wiley   +1 more source

Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin, Yen‐Bing Liu, Li‐Ting Ho, Ching‐Hua Kuo, Yu‐Fong Peng, Chih‐Fen Huang, Sung‐Chun Tang, Jiann‐Shing Jeng   +7 more
wiley   +1 more source

Central nervous system cavernous malformations: cross‐sectional study assessing rebleeding risk after a second haemorrhage

European Journal of Neurology, Volume 30, Issue 1, Page 144-149, January 2023., 2023
During an untreated 5‐year follow‐up after second hemorrhage, we identified a significantly increased risk of a third hemorrhage compared to the known risk of a first and second bleeding event. This risk was stratified according to different characteristics. Third bleeding was significantly associated with neurological deterioration.
Alejandro N. Santos, Laurèl Rauschenbach, Hanah Hadice Gull, Angelina Olbrich, Kirstin Lahl, Marvin Darkwah Oppong, Thiemo F. Dinger, Christoph Rieß, Bixia Chen, Annika Lenkeit, Börge Schmidt, Yan Li, Ramazan Jabbarli, Karsten H. Wrede, Ulrich Sure, Philipp Dammann   +15 more
wiley   +1 more source

Related factors of early mortality in young adults with cerebral hemorrhage

Open Medicine, 2018
The main causes of intracerebral hemorrhage differ between young adults and older adults. Data regarding potential targets for early intervention in young adult patients with intracerebral hemorrhage are lacking.
Zhou Hong Xia, Hao Nina, Xu Xiao Lin
doaj   +1 more source

Blood levels of glial fibrillary acidic protein (GFAP) in patients with neurological diseases. [PDF]

PLoS ONE, 2013
BACKGROUND AND PURPOSE: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Christoph A Mayer, Robert Brunkhorst, Marion Niessner, Waltraud Pfeilschifter, Helmuth Steinmetz, Christian Foerch   +5 more
doaj   +1 more source

Weakly supervised deep learning-based intracranial hemorrhage localization [PDF]

arXiv, 2021
Intracranial hemorrhage is a life-threatening disease, which requires fast medical intervention. Owing to the duration of data annotation, head CT images are usually available only with slice-level labeling. This paper presents a weakly supervised method of precise hemorrhage localization in axial slices using only position-free labels, which is based ...
arxiv