Results 71 to 80 of about 202,020 (287)
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
???INTRACEREBRAL HEMORRHAGE IN THE YOUNG.??? [PDF]
The Journal of Nervous and Mental Disease, 1887 n ...
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Advanced Science, EarlyView.Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
wiley +1 more source
BMC Neurology, 2018 Background Intracerebral hemorrhage is a devastating disease with no specific treatment modalities. A significant proportion of patients with intracerebral hemorrhage are transferred to large stroke treatment centers, such as Comprehensive Stroke Centers,
Farhaan S. Vahidy +13 more
doaj +1 more source
Lobar Intracerebral Hemorrhage
, 2000 Although intracerebral hemorrhage is a less frequent cause of stroke than cerebral infarction, it is more often fatal. It is usually attributed to hypertensive small-vessel disease, and the most common sites of hemorrhage are the basal ganglia ...
Sacco, Ralph L
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State of the art in managing nontraumatic intracerebral hemorrhage
, 2011 Nontraumatic intracerebral hemorrhage constitutes a major public health problem worldwide. Intracerebral hemorrhage leads to a high rate of morbidity and mortality.
Julie Dubourg, Mahmoud Messerer
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Advanced Science, EarlyView.Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng +7 more
wiley +1 more source
Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning
Advanced Science, EarlyView.Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin +13 more
wiley +1 more source
Cerebrovascular Diseases ExtraBackground: Compared to ischemic stroke, intracerebral hemorrhage (ICH) has higher mortality and more severe disability. Asian such as Chinese and Japanese and Mexican Americans, Latin Americans, African Americans, Native Americans has higher incidences than do white Americans. So, ICH is an important cerebrovascular disease in Asia.
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Risk of intracranial (including intracerebral) hemorrhage with low-dose aspirin.
, 2016 Data are shown as adjusted OR, multivariate HR or adjusted IRR, plus 95% CIs, for the risk of intracranial (including intracerebral) hemorrhage with low-dose aspirin vs no aspirin. A test for heterogeneity (I2 statistic) is provided.
Angel Lanas (15047) +4 more
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