Results 41 to 50 of about 5,738 (131)

Association between Plasma Adipocytokines Levels and Intracranial versus Extracranial Atherosclerotic among Chinese Patients with Stroke

Iranian Journal of Public Health, 2020
Background: To detect the levels of plasma Adipocytokines, TNF-α, IL-6 and PAI-1 in patients with intracranial and extracranial arteriosclerosis. Methods: From September 2015 to September 2017, 318 patients aged ≥60 years were enrolled.
Chunyu LIU, Xiaodan YANG, Changqing CHEN
doaj  

Intracranial arterial calcification and cerebrovascular function in the general aging population – A 7T MRI Study

Cerebral Circulation - Cognition and Behavior
Background: Intracranial arteriosclerosis may impair downstream cerebrovascular function, but the underlying mechanisms remain unclear. Using 7T MRI, we investigate the association between intracranial arteriosclerosis and cerebrovascular function in the
Anna M. Streiber, Carmen Kuenen, Stanley D.T. Pham, Julia Neitzel, Daniel Bos, Jeroen C.W. Siero, Jaco J.M. Zwanenburg, Nikki Dieleman, Geert Jan Biessels, Meike W. Vernooij   +9 more
doaj   +1 more source

High Prevalence of Cerebrovascular Calcifications and Clinical Correlates in Indigenous Bolivian Forager‐Horticulturalists: A Population‐Based Observational Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intracranial arteriosclerosis (large‐ and small‐vessel disease) is considered a risk factor for major neurological disorders, such as stroke, cognitive impairment, and dementia.
Giuseppe Barisano, Bavrina Bigjahan, Grant Schleifer, Maria Ashna, Wendy J. Mack, M. Linda Sutherland, James D. Sutherland, Helena C. Chui, Meng Law, Thomas J. Fischbach, Andrei Irimia, Nikhil N. Chaudhari, Daniel K. Cummings, Paul L. Hooper, Jacob E. Aronoff, Ellen E. Walters, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Jesus Bani Cuata, Kenneth Buetow, Caleb E. Finch, Michael D. Gurven, Jonathan Stieglitz, Gregory S. Thomas, Randall C. Thompson, Benjamin C. Trumble, Hillard Kaplan, Margaret Gatz   +27 more
doaj   +1 more source

The Added Prognostic Value of Intracranial Artery Morphology to Predict Non-Cardioembolic Ischemic Stroke

대한영상의학회지, 2018
Purpose: To assess the added prognostic value of the morphologic characteristics of intracranial arteries in the risk modeling of a future non-cardioembolic stroke.
Na Hye Han, Jinhee Jang, Hokyun Byun, Kijeong Lee, Jaseong Koo, Hyun Seok Choi, So-Lyung Jung, Kook-Jin Ahn, Bum-soo Kim   +8 more
doaj   +1 more source

Anticoagulant or Antithrombotic Therapy After Early Neurological Deterioration in Patients With Branch Atheromatous Disease Receiving Dual Antiplatelet Therapy

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective We evaluated the effectiveness and safety of adding tirofiban or argatroban after early neurological deterioration (END) in patients with branch atheromatous disease (BAD) receiving dual antiplatelet therapy and compared the outcomes with those of patients who continued dual antiplatelet therapy alone. Methods This retrospective study focused
Xuemin Zhong, Juan Yang, Ronghua Xu, Jian Wang, Nikhat Kaura   +4 more
wiley   +1 more source

Efficacy and safety of balloon dilation versus stent implantation in young ischemic stroke patients with symptomatic intracranial artery stenosis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To compare the efficiency and safety between balloon dilation and stent implantation in young ischemic stroke patients with symptomatic intracranial artery stenosis (ICAS).
ZHANG He, YU Lin⁃jie, ZHANG Xi, LUO Yun, XU Yun, LI Jing⁃wei   +5 more
doaj   +1 more source

Tmax volume can predict clinical type in patients with acute ischemic stroke

Brain and Behavior, 2023
Objective Endovascular therapy (EVT) is performed for acute ischemic stroke (AIS) with large vessel occlusion (LVO), however, the treatment strategies and clinical outcomes differ between cardiac embolism (CE) and intracranial arteriosclerosis‐derived ...
Fumihisa Kishi, Ichiro Nakagawa, Seigo Kimura, Daiji Ogawa, Ryokichi Yagi, Keiichi Yamada, Hirokatsu Taniguchi   +6 more
doaj   +1 more source

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

Association between homocysteine and white matter hyperintensities in rural‐dwelling Chinese people with asymptomatic intracranial arterial stenosis: A population‐based study

Brain and Behavior, 2021
Purpose Although homocysteine (Hcy) has been proven to be associated with the incidence of white matter hyperintensities (WMH) in patients with stroke, this association remains unclear in participants with asymptomatic intracranial arterial stenosis ...
Xiang Wang, Hao Yin, Xiaokang Ji, Shaowei Sang, Sai Shao, Guangbin Wang, Ming Lv, Fuzhong Xue, Yifeng Du, Qinjian Sun   +9 more
doaj   +1 more source

Plasma and neuroimaging biomarkers of small vessel disease and Alzheimer's disease in a diverse cohort: MESA [PDF]

Alzheimers Dement
Abstract INTRODUCTION Little is known about how Alzheimer's disease (AD) plasma biomarkers relate to cerebral small vessel disease (cSVD) neuroimaging biomarkers. METHODS The study involved 251 Wake Forest Multi‐Ethnic Study of Atherosclerosis (MESA) Exam 6 participants with plasma AD biomarkers, magnetic resonance imaging, amyloid positron emission ...
Lockhart S, Sutphen C, Tanley J, Gonzalez‐Ortiz F, Kac P, Habes M, Heckbert S, Ashton N, Mielke M, Koeppe R, Rudolph M, Sai K, Whitlow C, Hiatt K, Craft S, Register T, Hayden K, Rapp S, Sachs B, Zetterberg H, Blennow K, Karikari T, Hughes T.   +22 more
europepmc   +2 more sources