Results 101 to 110 of about 374,471 (348)

Global traumatic brain injury intracranial pressure: from monitoring to surgical decision

open access: yesFrontiers in Neurology
Traumatic brain injury (TBI) is a significant global public health issue, heavily impacting human health, especially in low-and middle-income areas. Despite numerous guidelines and consensus statements, TBI fatality rates remain high. The pathogenesis of
Dan Zhang   +4 more
doaj   +1 more source

Impact of Intracranial Pressure Monitoring on Prognosis of Patients With Severe Traumatic Brain Injury

open access: yesMedicine, 2016
To evaluate the influences of using intracranial pressure (ICP) monitoring on the prognosis of patients with severe traumatic brain injury.Systematic search were conducted in PubMed, Embase, Cochrane Library, Wanfang, and CNKI.
Jinsong Han   +4 more
semanticscholar   +1 more source

What went wrong? The flawed concept of cerebrospinal venous insufficiency [PDF]

open access: yes, 2013
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the central nervous system is associated with multiple sclerosis (MS), coining the term of chronic cerebrospinal venous insufficiency ('CCSVI'). The diagnosis of 'CCSVI' is
Al-Omari MH   +22 more
core   +2 more sources

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

open access: yesAdvanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang   +12 more
wiley   +1 more source

Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke?: an analysis of placebo-treated patients from prospective acute stroke trials [PDF]

open access: yes, 2008
<p><b>Background and Purpose:</b> The influence of stroke lateralization on functional and cardiovascular outcome after stroke is not well established.
Fink, J.N.   +3 more
core   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

Brain herniation in a patient with apparently normal intracranial pressure: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Intracranial pressure monitoring is commonly implemented in patients with neurologic injury and at high risk of developing intracranial hypertension, to detect changes in intracranial pressure in a timely manner.
Dahlqvist Mats B   +5 more
doaj   +1 more source

Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study

open access: yesLancet Neurology, 2021
C. Robba   +210 more
semanticscholar   +1 more source

A trial of intracranial pressure monitoring in traumatic brain injury

open access: yesCritical Care, 2014
BACKGROUND Intracranial pressure (ICP) monitoring is considered the standard of care for severe traumatic brain injury (TBI) and is used frequently, but the efficacy of treatment based on monitoring in improving the outcome has not been rigorously ...
S. Melhem, L. Shutter, A. M. Kaynar
semanticscholar   +1 more source

A Metalloporphyrin Nanosystem Enables Non‐Invasive Visualization and Specific Treatment for Thrombosis and Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
Thrombotic ischemic stroke is a severe neurological disease of the brain that presents major challenges for effective diagnosis and treatment. Precisely engineered Ir and Mn cores within a single porphyrin framework of 4IrMn nanoparticles enable endogenous ONOO−‐ or laser‐activated switching among NIR‐CL imaging, photothermal / photodynamic therapy ...
Ziwei Wang   +10 more
wiley   +1 more source

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