Results 151 to 160 of about 37,015 (229)

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Updated European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies guidelines for the management of rectosigmoid Hirschsprung's disease 2025

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 1, Page 185-207, July 2026.
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi   +35 more
wiley   +1 more source

De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects

open access: yesMedComm, Volume 7, Issue 7, July 2026.
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley   +1 more source

Specialty‐Based Disparities in Biologic Use and Retention in Psoriatic Arthritis: A Nationwide Korean Claims Analysis

open access: yesInternational Journal of Rheumatic Diseases, Volume 29, Issue 7, July 2026.
ABSTRACT Aim Biologic agents play a pivotal role in controlling both articular and cutaneous manifestations of psoriatic arthritis (PsA). Although international guidelines emphasize the appropriate use of biologics, Korea lacks standardized treatment protocols tailored for PsA across specialties.
Bon San Koo   +4 more
wiley   +1 more source

Treating Chronic, Intractable Pain with a Miniaturized Spinal Cord Stimulation System: 1-Year Outcomes from the AUS-nPower Study During the COVID-19 Pandemic. [PDF]

open access: yesJ Pain Res
Salmon J   +13 more
europepmc   +1 more source

Psilocybin as a novel treatment for chronic pain

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 14, Page 3992-4005, July 2026.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey   +3 more
wiley   +1 more source

Enabling Nature‐Based Solutions by Embracing Their Limits: Insights From Governing in Complexity

open access: yesConservation Letters, Volume 19, Issue 4, July/August 2026.
ABSTRACT Nature‐based solutions (NbS) have become a central concept in contemporary conservation. While much scholarship and practice aim to refine and upscale NbS, we argue that it is important to recognize their inherent limits, which stem from the complexity of socio‐ecological systems.
Kerry A. Waylen, Rakhyun E. Kim
wiley   +1 more source

‘AN AUSTRIAN FATE’: TRAUMA, REPRESSION AND WAR IN ADRIAN GOIGINGER'S DER FUCHS (2022)

open access: yesGerman Life and Letters, Volume 79, Issue 3, Page 351-364, July 2026.
ABSTRACT This article examines one of the highest‐grossing films in recent years in Austria, Der Fuchs (Adrian Goiginger, 2022), which focuses on the friendship of the protagonist, a Wehrmacht soldier, with an abandoned fox cub, but in the process elides more than four years of the soldier's wartime experience.
Katya Krylova
wiley   +1 more source

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