Resting-state brain functional connectivity in patients with chronic intractable pain who respond to spinal cord stimulation therapy. Comment on Br J Anaesth 2025; 134: 492-500. [PDF]
Zhou PB, Bao M, Sun HT.
europepmc +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi +35 more
wiley +1 more source
Successful radiofrequency thermocoagulation of the mandibular nerve for intractable pain associated with medication-related osteonecrosis of the jaw: a case report. [PDF]
Shinotsuka S +6 more
europepmc +1 more source
De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley +1 more source
ABSTRACT Aim Biologic agents play a pivotal role in controlling both articular and cutaneous manifestations of psoriatic arthritis (PsA). Although international guidelines emphasize the appropriate use of biologics, Korea lacks standardized treatment protocols tailored for PsA across specialties.
Bon San Koo +4 more
wiley +1 more source
Treating Chronic, Intractable Pain with a Miniaturized Spinal Cord Stimulation System: 1-Year Outcomes from the AUS-nPower Study During the COVID-19 Pandemic. [PDF]
Salmon J +13 more
europepmc +1 more source
Psilocybin as a novel treatment for chronic pain
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey +3 more
wiley +1 more source
Enabling Nature‐Based Solutions by Embracing Their Limits: Insights From Governing in Complexity
ABSTRACT Nature‐based solutions (NbS) have become a central concept in contemporary conservation. While much scholarship and practice aim to refine and upscale NbS, we argue that it is important to recognize their inherent limits, which stem from the complexity of socio‐ecological systems.
Kerry A. Waylen, Rakhyun E. Kim
wiley +1 more source
‘AN AUSTRIAN FATE’: TRAUMA, REPRESSION AND WAR IN ADRIAN GOIGINGER'S DER FUCHS (2022)
ABSTRACT This article examines one of the highest‐grossing films in recent years in Austria, Der Fuchs (Adrian Goiginger, 2022), which focuses on the friendship of the protagonist, a Wehrmacht soldier, with an abandoned fox cub, but in the process elides more than four years of the soldier's wartime experience.
Katya Krylova
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