The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy [PDF]
Breckpot, Karine +6 more
core +1 more source
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani +4 more
wiley +1 more source
Botulinum Toxin Type A in the Treatment of Primary Axillary Hyperhidrosis:A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety in Chinese Patients. [PDF]
Li Y +12 more
europepmc +1 more source
ABSTRACT Background Hyaluronic acid (HA) and Botulinum toxin A (BTX‐A) treatments are highly regarded for their effectiveness in facial rejuvenation. Aim To investigate whether adding Profhilo enhances the effects of BTX‐A for frontal skin rejuvenation.
Zahra Saffarian +9 more
wiley +1 more source
Human Derived Exosome Injections (ASCE+ vs. CELLEXOSOME) Enhance Collagen Remodeling and Angiogenesis in Intact Skin: A Comparative Experimental Study. [PDF]
Adel N +10 more
europepmc +1 more source
Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer
ABSTRACT Background The convergence of nanotechnology and immunotherapy has ushered in a transformative era in cancer treatment, offering new strategies to overcome pharmacokinetic limitations and immune evasion associated with conventional therapies. While immunotherapy, spanning checkpoint inhibitors, adoptive cell transfer, and cancer vaccines, has ...
Nima Javanmehr +4 more
wiley +1 more source
Intradermal Acupuncture for Moderate to Severe Dry Eye Disease: a pilot randomized controlled trial. [PDF]
Park SY.
europepmc +1 more source
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li +9 more
wiley +1 more source
Beyond barrier function: keratinocytes as orchestrators of humoral immunity. [PDF]
Guo C, Tsokos GC.
europepmc +1 more source
Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk +9 more
wiley +1 more source

