Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH. [PDF]
J Cosmet DermatolAlJabr A, AlAnazi AMI, AlEtebi RAA.
europepmc +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
British Journal of Pharmacology, Volume 183, Issue 11, Page 3015-3031, June 2026.A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
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Contact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli +8 more
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Intramuscular versus intradermal administration of fractional dose inactivated poliovirus vaccine in Mozambique, 2020-2022: an, open-label, non-inferiority, randomised, controlled phase 2 trial. [PDF]
EClinicalMedicineOmar Viegas E +11 more
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Immunology, Volume 178, Issue 2, Page 307-317, June 2026.Eight percent of this cohort of patients had a latent Neoehrlichia mikurensis infection. It was only the latently infected patients who had N. mikurensis‐specific T cells, not the matched B‐cell lymphoma patients without the infection. The T‐cell responses of latently infected patients included perforin‐expressing Th1 and CD8+ T cells that upregulated ...
Linda Wass +4 more
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Comparison of Immune Cell Transfection by Different Vaccine Vectors After Intradermal Injection. [PDF]
Vaccines (Basel)Liu J +6 more
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Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, Volume 20, Issue 5, Page 1093-1097, May 2026.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
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Subcuticular suture achieves better esthetics, healing, and similar functional outcomes following unicompartmental knee arthroplasty: a single center retrospective comparative study. [PDF]
Front Med (Lausanne)Huang C +6 more
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TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
Advanced Science, Volume 13, Issue 25, 4 May 2026.TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
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