Circuit dissection of the role of somatostatin in itch and pain [PDF]
Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which this occurs is still poorly understood.
AJ Christensen +79 more
core +1 more source
Hyperhidrosis, or excessive sweating, negatively impacts patients both physically and psychologically. It may be primary or secondary: the primary form is a benign condition, with its growing prevalence reaching 5% recently.
Ghadah Alhetheli
doaj +1 more source
Comparative evaluation of [(99m)tc]tilmanocept for sentinel lymph node mapping in breast cancer patients: results of two phase 3 trials. [PDF]
BackgroundSentinel lymph node (SLN) surgery is used worldwide for staging breast cancer patients and helps limit axillary lymph node dissection.
Avisar, Eli +15 more
core +2 more sources
Preprotachykinin A (PPTA) is expressed by a distinct population of excitatory neurons in the mouse superficial spinal dorsal horn including cells that respond to noxious and pruritic stimuli [PDF]
The superficial dorsal horn, which is the main target for nociceptive and pruritoceptive primary afferents, contains a high density of excitatory interneurons.
Bell, Andrew M. +8 more
core +1 more source
Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core +1 more source
Vasoconstrictor Potency of Corticoids: Intradermal Injection
Studies of topical corticoid vasoconstriction involve both percutaneous penetration and inherent vasoconstrictor activity. In order to eliminate the penetration aspect, a study of steroid action intradermally was undertaken. Serial dilutions of hydrocortisone, prednisolone, triamcinolone, dexamethasone acetate, dexamethasone, triamcinolone acetonide ...
Sutton, Pamela M +2 more
openaire +2 more sources
Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA
Local administration of naked self-replicating mRNA (sr-mRNA) in the skin or muscle using electroporation is effective but hampered by low repeatability.
Hanne Huysmans +6 more
doaj +1 more source
In recent years, tattooing technology has shown promising results toward evaluating vaccines in both animal models and humans. However, this technology has some limitations due to variability of experimental evaluations or operator procedures.
Alejandro M. Gomez +11 more
doaj +1 more source
Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]
BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M +5 more
core +2 more sources
Immunogenicity, safety and tolerability of intradermal influenza vaccines
Intradermal influenza vaccination has been studied for more than 80 y. The revived interest in this strategy of vaccination is a result of the innovative technologies in needle design allowing more precise injection and making the device easier to use ...
Ivan F. N. Hung, Kwok-Yung Yuen
doaj +1 more source

