Results 31 to 40 of about 49,583 (285)

Immune response to vaccines in children with celiac disease [PDF]

, 2017
Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina, CHIESA, CLAUDIO, OLIVERO, FRANCESCA, PACIFICO, Lucia, Spagnolo, Alessandra   +4 more
core   +1 more source

An intradermal inoculation model of scrub typhus in Swiss CD-1 mice demonstrates more rapid dissemination of virulent strains of Orientia tsutsugamushi.

PLoS ONE, 2013
Scrub typhus is an important endemic disease of the Asia-Pacific region caused by Orientia tsutsugamushi. To develop an effective vaccine to prevent scrub typhus infection, a better understanding of the initial host-pathogen interaction is needed.
Piyanate Sunyakumthorn, Daniel H Paris, Teik-Chye Chan, Margaret Jones, Alison Luce-Fedrow, Suchismita Chattopadhyay, Ju Jiang, Tippawan Anantatat, Gareth D H Turner, Nicholas P J Day, Allen L Richards   +10 more
doaj   +1 more source

Evaluation of Challenge Models for Flavobacterium covae Infection of Grass Carp (Ctenopharyngodon idellus)

Microorganisms
Columnaris disease is a highly contagious infection that affects nearly all freshwater fish species worldwide. Grass carp, one of the most economically significant freshwater fish species in China, is particularly susceptible to the disease, leading to ...
Rui Han, Huicheng Wu, Zhongning He, Zequan Mo, Xueming Dan, Yanwei Li   +5 more
doaj   +1 more source

Safety evaluation of a buffer used in the lyophilization of canine platelets: type I hypersensitivity reaction in dogs caused by bovine serum albumin

Frontiers in Veterinary Science
IntroductionThe present study was designed to evaluate the safety of substances generally used in the preparation of lyophilized platelet products (LPPs) because the possibility of an immune response to bovine serum albumin (BSA) was considered high when
Hee-Jae Choi, Mu-Young Kim, Hyun-Jung Han, Hyun-Jung Han   +3 more
doaj   +1 more source

Cellular immune responses induced with dose-sparing intradermal administration of HIV vaccine to HIV-uninfected volunteers in the ANRS VAC16 trial. [PDF]

PLoS ONE, 2007
The objective was to compare the safety and cellular immunogenicity of intradermal versus intramuscular immunization with an HIV-lipopeptide candidate vaccine (LIPO-4) in healthy volunteers.A randomized, open-label trial with 24 weeks of follow-up was ...
Odile Launay, Christine Durier, Corinne Desaint, Benjamin Silbermann, Angela Jackson, Gilles Pialoux, Bénédicte Bonnet, Isabelle Poizot-Martin, Gustavo Gonzalez-Canali, Lise Cuzin, Suzanne Figuereido, Mathieu Surenaud, Nadine Ben Hamouda, Hanne Gahery, Jeannine Choppin, Dominique Salmon, Corinne Guérin, Isabelle Bourgault Villada, Jean-Gérard Guillet, ANRS VAC16 Study Group   +19 more
doaj   +1 more source

Spinal neurons that contain gastrin-releasing peptide seldom express Fos or phosphorylate extracellular signal-regulated kinases in response to intradermal chloroquine [PDF]

, 2016
Background: Gastrin-releasing peptide (GRP) is thought to play a role in the itch evoked by intradermal injection of chloroquine. Although some early studies suggested that GRP was expressed in pruriceptive primary afferents, it is now thought that GRP ...
Bell, Andrew M., Gutierrez-Mecinas, Maria, Polgár, Erika, Todd, Andrew J.   +3 more
core   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Progress of Psoralea corylifolia injection in the treatment of vitiligo

Pifu-xingbing zhenliaoxue zazhi, 2023
Vitiligo is a common skin disease with acquired depigmentation, seriously impacting patients′ physical and mental health. With the acceleration of life rhythm and the increase in psychological stress, the incidence of vitiligo increases.
Han LIU, Mudiao CHEN, Yongbin QU
doaj   +1 more source

Kounis Syndrome Associated With Selective Anaphylaxis to Cefazolin. [PDF]

, 2018
info:eu-repo/semantics ...
Chambel, M, Correia, M, Gaspar, A, Morais-Almeida, M, Mota, I, Sequeira, T   +5 more
core   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source