Results 51 to 60 of about 49,583 (285)

Mid-term results of autoinjection therapy for erectile dysfunction [PDF]

, 1988
Of over 300 patients with erectile dysfunction, 186 were selected for intracavernosal autoinjection therapy with a standardized papaverine-phentolamine mixture.
Brindley, Brindley, Christian G. Stief, Dhabuwala, Helmuth Gall, Klinge, Larsen, Lue, Robinette, Sidi, Stief, Stief, Virag, Wolfgang Bahren, Wolfgang Scherb, Zorgniotti, Zorgniotti   +16 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A Pilot Study of Differences in Antibody Responses of Intradermal and Intramuscular Injections of Botulinum Toxin Type A

Dermatology and Therapy
Introduction Botulinum toxin type A (BoNT/A) is commonly used for both medical and aesthetic purposes. However, approximately 3% of long-term recipients develop resistance, potentially due to antibody formation.
Yuttana Srinoulprasert, Surachet Sirisuthivoranunt, Chattip Sripatumtong, Tunsuda Tansit, Chadakan Yan, Chalermkwan Apinuntham, Thanya Techapichetvanich, Sasima Eimpunth, Woraphong Manuskiatti, Rungsima Wanitphakdeedecha   +9 more
doaj   +1 more source

Comparison of antibody titres between intradermal and intramuscular rabies vaccination using inactivated vaccine in cattle in Bhutan : a thesis presented in the partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]

, 2018
In developing countries, the cost of vaccination limits the use of prophylactic rabies vaccination, especially in cattle. Intradermal vaccination delivers antigen directly to an area with higher number of antigen-presenting cells.
Wangmo, Karma
core  

Co-Localization of p-CREB and p-NR1 in Spinothalamic Neurons in a Chronic Muscle Pain Model [PDF]

, 2007
Activation of the cAMP pathway is an important mediator of chronic muscle pain. This study examined phosphorylation of the transcription factor cAMP-response-element-binding protein (p-CREB) and the NR1 subunit of the NMDA receptor (p-NR1) in the spinal ...
Bement, Marie K. Hoeger, Sluka, Kathleen A.   +1 more
core   +2 more sources

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Safety and efficacy of mesotherapy in musculoskeletal disorders: A systematic review of randomized controlled trials with meta-analysis

Journal of Rehabilitation Medicine, 2021
Objectives: To conduct a systematic review of randomized controlled trials about the safety (number and severity of adverse events) and efficacy (pain reduction and functional improvement) of mesotherapy in musculoskeletal disorders, and to compare them ...
Lorenzo Faetani, Daniele Ghizzoni, Antonio Ammendolia, Cosimo Costantino   +3 more
doaj   +1 more source

Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]

, 1993
Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E., Kanagawa, Osami, Osman, Gamal-E, Toda, Masaaki   +3 more
core   +2 more sources

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Clinical evaluation of the efficacy of Amalian SF intradermal implants with lidocaine: results of a multicenter study

Vestnik Dermatologii i Venerologii
Background. An increasing number of hyaluronic acid-based products are available in the Russian Federation, which necessitates studies to confirm the efficacy and safety of these new products. Aim.
M. V. Zhuchkov, Soo Whan Choi
doaj   +1 more source