Results 91 to 100 of about 16,684 (214)

Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles

Pharmaceutical Research
Abstract Purpose A dissolving microneedle array (dMNA) is a vaccine delivery device with several advantages over conventional needles. By incorporating particulate adjuvants in the form of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) into the dMNA, the immune response against the antigen might be enhanced.
Lee, J., Neustrup, M.A., Slütter, B.A., O'Mahony, C., Bouwstra, J.A., Maaden, K. van der   +5 more
openaire   +4 more sources

Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]

, 2013
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin, Champer, Jackson, Friedman, Adam J, Kim, Jenny, Liu, Phil T, Modlin, Robert L, Oren, Ami, Phan, Jenny, Pirouz, Aslan, Qin, Min, Schairer, David O   +10 more
core   +1 more source

Microneedles for the treatment of migraine and orofacial pain: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1148-1161, May 2026.
Abstract Background Migraine is a common neurological disorder and a primary headache condition. Despite its central origin, migraine pain may be referred to the orofacial region via trigeminal pathways, resulting in phenotypic overlap with other orofacial pain (OFP) conditions.
Baicheng Cao, Qiuyi Chen, Yuhan Liu, Ruozhou Wu, Bin Li, Qing Cai, Lu Liu   +6 more
wiley   +1 more source

Persistence of pain induced by startle and forehead cooling after sympathetic blockade in patients with complex regional pain syndrome [PDF]

, 2004
Background: Stimuli arousing sympathetic activity can increase ratings of clinical pain in patients with complex regional pain syndrome (CRPS). Objective: To determine whether the increase in pain is mediated by peripheral sympathetic activity.
Drummond, P.D., Finch, P.M.
core   +1 more source

Self-Reported Occupational Exposure to HIV and Factors Influencing its Management Practice: A Study of Healthcare Workers in Tumbi and Dodoma Hospitals, Tanzania. [PDF]

, 2013
Blood borne infectious agents such as hepatitis B virus (HBV), hepatitis C virus (HCV) and human immune deficiency virus (HIV) constitute a major occupational hazard for healthcare workers (HCWs).
A Karstaedt, A Sharma, B Doebbeling, B Gumodoka, B Shariati, C Denise, C Lin, C Sagoe-Moses, CM Mangione, D Strader, F Pont, FM Nsubuga, G Bennet, G Frijstein, Godfrey M Mubyazi, Government of India, Hamisi M Malebo, Hussein Mohamed, JL Gerberding, K Twitchell, Kijakazi O Mashoto, M Zhang, MM Chagani, MMWR, RC Merchant, SK Lwanga, SV Manyele, WHO, Y Hutin   +28 more
core   +1 more source

Efficacy and Safety of Non‐Cross‐Linked Hyaluronic Acid Mesotherapy for Post‐Acne Erythema: A Split‐Face, Prospective, Randomized, Single‐Center Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Post‐acne erythema (PAE) is one of the most common inflammatory sequelae of acne. Although various therapeutic approaches are currently available, many are limited by suboptimal efficacy, poor tolerability, or high costs. This trial aims to evaluate the clinical efficacy and safety of non‐cross‐linked hyaluronic acid (HA ...
Di Zhang, Yuan Chang, Yue Bai, Ansheng Tan, Zixuan He, Yu Han, Anxin Chen, Fenglin Zhuo   +7 more
wiley   +1 more source

Comparative field efficacy of all-in-one intradermal vaccine based on an inactivated recombinant Mycoplasma hyopneumoniae with an embedded/integrated porcine circovirus type 2 (PCV2) capsid protein and concurrent administration with monovalent of M. hyopneumoniae and PCV2 intradermal vaccine

Frontiers in Veterinary Science
BackgroundEfficacy of an intradermal all-in-one vaccine based on an inactivated recombinant Mycoplasma hyopneumoniae strain with an embedded/integrated porcine circovirus type 2 (PCV2) capsid protein thereof, as the single active substance, is provided ...
Jeongmin Suh, Sehyeong Ham, Chanhee Chae
doaj   +1 more source

Hyaluronic Acid Dermal Filler‐Associated Vascular Occlusion—A Review of Prevention and Management Strategies

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Significant complications are uncommon with aesthetic hyaluronic acid (HA) dermal fillers, but inadvertent injection of dermal filler into an artery can result in tissue damage, scarring, visual loss, and even stroke. Practitioners must therefore reduce this risk through proactive, preventative techniques.
Stephen Lowe
wiley   +1 more source

Intradermal delivery of a fractional dose of influenza H7N9 split vaccine elicits protective immunity in mice and rats

Human Vaccines & Immunotherapeutics, 2018
Vaccination is the most effective method of preventing the spread of the influenza virus. However, the traditional intramuscular (IM) immunization causes fear, pain, and cross infection.
Shanshan Zhou, Tianyu Ren, Hongjing Gu, Cheng Wang, Min Li, Zhongpeng Zhao, Li Xing, Liangyan Zhang, Yi Sun, Penghui Yang, Xiliang Wang   +10 more
doaj   +1 more source

Inkjet printing of transdermal microneedles for the delivery of anticancer agents [PDF]

, 2015
A novel inkjet printing technology is introduced as a process to coat metal microneedle arrays with three anticancer agents 5-fluororacil, curcumin and cisplatin for transdermal delivery.
Arora, Babur Chowdhry, Bierwagen, Chabri, Chen, Chen, Choi, Chu, Dennis Douroumis, Donnelly, Donnelly, Gill, Graham, Henry, Hensel, Katikaneni, Kim, Kim, Kochhar, Larrañeta, Lee, Lee, Li, Lin, Maniruzzaman, Mark R. Prausnitz, McAllister, Md Jasim Uddin, Mulik, Nicolaos Scoutaris, Nir, Pavlos Klepetsanis, Simonsen, Tarcha, Tian, van der Maaden, Yan   +36 more
core   +1 more source